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Key Features

Recombinant ALIX Monoclonal Antibody (AGEL6712)

Datasheet MSDS
SKU AGEL6712
Product Type Antibody
Reactivity Human, Rat, Mouse
Applications WB, IHC, IP
Host Species Rabbit
Clonality Monoclonal
Clone C121407
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant ALIX Monoclonal Antibody

The Recombinant ALIX Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C121407) against ALIX. Programmed cell death 6-interacting protein (PDCD6IP), plays an important role in the endosomal sorting complexes required for transport (ESCRT) pathway in the abscission stage of cytokinesis and apoptosis. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the protein binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC and IP applications. It has been validated by WB analysis of HeLa, C6, Mouse brain, Rat brain, IHC analysis of Human breast cancer and IP analysis of HeLa cells extracts. The target is localized to the cytoskeleton, secreted, cytosol.

Product Name:Recombinant ALIX Monoclonal Antibody
SKU:AGEL6712
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:AIP, AIP1, ALIX, DRIP, DRIP4, HP95, KIAA, KIAA1375, PDCD6IP
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant human ALIX fragment
Applications:WBIHCIP
Clonality:Recombinant Monoclonal
Clone No:C121407
Host:Rabbit
Isotype:Rabbit IgG
Target:ALIX
Conjugation:Unconjugated
Observed MW:90/100 kDa
Calculated MW:96 kDa
Recommended Dilution:WB 1:2000-10000; IHC 1:100-500; IP 1:25-50
UniProt:Q8WUM4
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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