The Recombinant ApoER2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C733316) against ApoER2. Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Rat and Hamster samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of CHO-K1, C6.