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Recombinant ASGPR1 Monoclonal Antibody (RMEA0151)

Datasheet MSDS
SKU RMEA0151
Product Type Antibody
Reactivity Human
Applications WB, IHC-P, ICC/IF, FC, IP
Host Species Rabbit
Clonality Monoclonal
Clone C310137
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant ASGPR1 Monoclonal Antibody

The Recombinant ASGPR1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C310137) against ASGR1. This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB, IHC-P, ICC/IF, FC and IP applications. It has been validated by IF analysis of HepG2.

Product Name:Recombinant ASGPR1 Monoclonal Antibody
SKU:RMEA0151
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:ASGP-R, ASGP-R 1, ASGPR, ASGPR 1, ASGPR1, ASGR, ASGR1, Asialoglycoprotein receptor 1, C type lectin domain family 4 member H, C type lectin domain family 4 member H1, C-type lectin domain family 4 member H1, CLEC4H, CLEC4H1, Hepatic lectin H1, HL-1
Reactivity:Human
Immunogen:Recombinant Human ASGPR1 protein
Applications:WBIHC-PICC/IFFCIP
Clonality:Recombinant Monoclonal
Clone No:C310137
Host:Rabbit
Isotype:Rabbit IgG
Target:ASGR1
Conjugation:Unconjugated
Observed MW:42 kDa
Calculated MW:33 kDa
Recommended Dilution:WB 1:1000; IHC-P: 1:200-1000; ICC/IF: 1:100; FC: 1:200-500; IP: 1:20-50
UniProt:P07306
Purification:Protein A
Concentration:1 mg/mL
Buffer:0.2 µm filtered solution in PBS
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Product ImageImmunofluorescence analysis of HepG2 cells labelling ASGR1. The cells were fixed with cold 100% methanol 4℃) (10min, and blocked in 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween 20 for 1h. The cells were then incubate with (1:100) at room temprature for 1h, followed by a further incubation at room temperature for 45min with Goat Anti Rabbit lgG (H+L)- AF488 (shown in green). Nuclear DNA was labeled in blue with DAPI. Control: Secondary antibody only.
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