The Recombinant ATG7 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110594) against ATG7. This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of Hela. The target is localized to the cytoplasm.
Product Name:
Recombinant ATG7 Monoclonal Antibody
SKU:
AGEL5908
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
1810013K23Rik, Apg 7, APG7, APG7 autophagy 7 like, APG7 autophagy 7-like (S. cerevisiae), APG7 like, APG7-LIKE, Apg7/Atg, Apg7/Atg7, APG7L, ATG, ATG 7, ATG12-activating enzyme E1 ATG7, ATG7, ATG7 autophagy related 7 homolog, ATG7 autophagy related 7 homolog (S. cerevisiae), Atg7l, Autophagy 7, Autophagy related protein 7, Autophagy-related 7 (yeast), Autophagy-related protein 7, DKFZp434N0735, GSA, GSA 7, GSA7, hAGP7, homolog of, S. cerevisiae, Ubiquitin activating enzyme E1 like protein, Ubiquitin-activating enzyme E1-like protein, Ubiquitin-like modifier-activating enzyme ATG7
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human ATG7 protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110594
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
ATG7
Conjugation:
Unconjugated
Observed MW:
78 kDa
Calculated MW:
78 kDa
Recommended Dilution:
IHC 1:200-1000; WB 1:1000-5000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
O95352
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.