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Key Features

Recombinant Axin 2 Monoclonal Antibody (AGEL8625)

Datasheet MSDS
SKU AGEL8625
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB
Host Species Rabbit
Clonality Monoclonal
Clone C133320
Conjugate Unconjugated
$461 - $632

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Description

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Recombinant Axin 2 Monoclonal Antibody

The Recombinant Axin 2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C133320) against Axin 2. The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB applications. It has been validated by WB analysis of K562, C6, 3T3, Hela. The target is localized to the cytoplasm.

Product Name:Recombinant Axin 2 Monoclonal Antibody
SKU:AGEL8625
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:AXIL, axin-2, AXIN2, ODCRCS
Reactivity:Human, Mouse, Rat
Immunogen:A synthetic peptide of human Axin 2
Applications:WB
Clonality:Recombinant Monoclonal
Clone No:C133320
Host:Rabbit
Isotype:Rabbit IgG
Target:Axin 2
Conjugation:Unconjugated
Observed MW:94 kDa
Calculated MW:94 kDa
Recommended Dilution:WB 1:500-1000
UniProt:Q9Y2T1
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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