The Recombinant B7-H3/CD276 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C211065) against B7-H3/CD276. May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human and Mouse samples.
This antibody is suitable for WB, IHC, IF, FCM and IP applications. It has been validated by WB analysis of HeLa, MCF-7, 293T, IHC analysis of Human cervical cancer, Human lung squamous carcinoma, Human tonsil, Mouse spleen, Mouse stomach, IF analysis of HeLa, THP-1, FCM analysis of THP-1, HeLa and IP analysis of HeLa cells extracts. The target is localized to the membrane.