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Recombinant Beclin 1 Monoclonal Antibody (AGEL8538)

Datasheet MSDS
SKU AGEL8538
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB
Host Species Rabbit
Clonality Monoclonal
Clone C133233
Conjugate Unconjugated
€349 - €479

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Description

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Recombinant Beclin 1 Monoclonal Antibody

The Recombinant Beclin 1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C133233) against Beclin 1. Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB applications. It has been validated by WB analysis of K562, Rat Rat Brain, C6, 3T3, Hela. The target is localized to the Golgi apparatus>trans-Golgi network membrane. Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells.

Product Name:Recombinant Beclin 1 Monoclonal Antibody
SKU:AGEL8538
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:APG6, ATG 6, ATG6, ATG6 autophagy related 6 homolog, Bcl-2-interacting protein beclin, Beclin 1 (coiled coil moesin like BCL2 interacting protein), Beclin 1 autophagy related, Beclin-1, Beclin1, BECN 1, BECN1, C, Coiled coil myosin like BCL2 interacting protein, Coiled-coil myosin-like BCL2-interacting protein, GT197, Protein GT197, VPS 30, VPS30
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant protein of human Beclin 1
Applications:WB
Clonality:Recombinant Monoclonal
Clone No:C133233
Host:Rabbit
Isotype:Rabbit IgG
Target:Beclin 1
Conjugation:Unconjugated
Observed MW:52 kDa
Calculated MW:52 kDa
Recommended Dilution:WB 1:500-1000
UniProt:Q14457
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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