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Key Features

Recombinant BMAL1 Monoclonal Antibody (AGEL5624)

SKU AGEL5624
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IHC, IF, IP, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C110305
Conjugate Unconjugated
$540 - $738

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Description

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Recombinant BMAL1 Monoclonal Antibody

The Recombinant BMAL1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110305) against BMAL1. The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC, IF, IP and ELISA applications. It has been validated by WB analysis of Rat brain. The target is localized to the nucleus.

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