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Key Features

Recombinant CBX4 Monoclonal Antibody (AGEL6742)

Datasheet MSDS
SKU AGEL6742
Product Type Antibody
Reactivity Human, Rat, Mouse
Applications WB, IHC
Host Species Rabbit
Clonality Monoclonal
Clone C121437
Conjugate Unconjugated
€459 - €639

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Description

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Recombinant CBX4 Monoclonal Antibody

The Recombinant CBX4 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C121437) against CBX4. CBX4 is a component of the PRC1 complex, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit. CBX4 itself is a SUMO E3 ligase, and its function influences EMT, DNA damage response, tumor angiogenesis, and self-renewal. E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of HepG2, C6 and IHC analysis of Human breast cancer, Human cerebrum, Mouse cerebrum, Mouse stomach, Rat cerebrum. The target is localized to the nucleus.

Product Name:Recombinant CBX4 Monoclonal Antibody
SKU:AGEL6742
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:Cbx, CBX4
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant human CBX4 fragment
Applications:WBIHC
Clonality:Recombinant Monoclonal
Clone No:C121437
Host:Rabbit
Isotype:Rabbit IgG
Target:CBX4
Conjugation:Unconjugated
Observed MW:61 kDa
Calculated MW:61 kDa
Recommended Dilution:WB(human) 1:500-1000; WB(rat) 1:1000-5000; IHC 1:200-1000
UniProt:O00257
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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