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Recombinant CD41 Monoclonal Antibody (AGEL6407)

Datasheet MSDS
SKU AGEL6407
Product Type Antibody
Reactivity Human
Applications WB
Host Species Rabbit
Clonality Monoclonal
Clone C331101
Conjugate Unconjugated
$606 - $843

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Description

system_update_altDatasheetsystem_update_altMSDS

Recombinant CD41 Monoclonal Antibody

The Recombinant CD41 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C331101) against CD41. Integrin α-IIb/β-3 (ITGA2B) is a cell surface adhesion molecule that is the receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. In activated platelets, ITGA2B can be cleaved by proteolytic enzymes to generate disulfide bond-connected heavy and light chains, and form fibrinogen receptors together with glycoprotein IIIb, causing platelet interactions and rapid platelet aggregation, thereby Block the surface of ruptured endothelial cells. The corresponding ITGA2B gene mutation can cause platelet weakness. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB applications. It has been validated by WB analysis of Human platelet. The target is localized to the cell membrane.

Product Name:Recombinant CD41 Monoclonal Antibody
SKU:AGEL6407
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:&amp, alpha 2b, alpha subunit, alpha-IIb integrin-n, antigen CD41, BDPLT16, BDPLT2, CD41, CD41B, form 2, GP2B, GPalpha Iib, GPIIb, GT, GTA, HPA, HPA3, Integrin, Integrin alpha 2b, Integrin alpha IIb, Integrin alpha-Iib, Integrin alpha-IIb light chain, integrin αIIbβ3, ITA2B, ITGA2B, ITGAB, platelet fibrinogen receptor, platelet glycoprotein IIb of IIb/IIIa complex, Platelet membrane glycoprotein Iib, platelet specific antigen BAK, PPP1R, PPP1R93
Reactivity:Human
Immunogen:Recombinant human CD41 fragment
Applications:WB
Clonality:Recombinant Monoclonal
Clone No:C331101
Host:Rabbit
Isotype:Rabbit IgG
Target:CD41
Conjugation:Unconjugated
Observed MW:128 kDa
Calculated MW:113 kDa
Recommended Dilution:WB 1:500-2000
UniProt:P08514
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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