The Recombinant CD89 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C310368) against CD89. This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB, IHC, IF, ICC, FC and IP applications. It has been validated by WB analysis of HL-60. The target is localized to the Cell membrane; Single-pass type I membrane protein, Cell membrane; Single-pass type I membrane protein, Cell membrane; Single-pass type I membrane protein, secreted, secreted.
Product Name:
Recombinant CD89 Monoclonal Antibody
SKU:
AGEL5686
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
CD89, CTB-61M, CTB-61M7.2, Fc alpha receptor, Fc fragment of IgA, Fc fragment of IgA receptor, FcalphaRI, FCAR, IgA Fc Receptor, IgA R, Immunoglobulin Alpha Fc Receptor, receptor for, XXbac-BPG230H, XXbac-BPG230H20.5
Reactivity:
Human
Immunogen:
Recombinant Human CD89 protein
Applications:
WBIHCIFICCFCIP
Clonality:
Recombinant Monoclonal
Clone No:
C310368
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
CD89
Conjugation:
Unconjugated
Observed MW:
32 kDa
Recommended Dilution:
WB 1:1000-5000; IHC 1:100-300; ICC/IF 1:100-300; FC 1:100-300; IP 1:50-100
UniProt:
P24071
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.