The Recombinant CLEC2D Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C331591) against CLEC2D. C-type lectin domain family 2 member D (CLEC2D), also known as lectin-like transcript 1 (LLT1) and osteoclast inhibitory lectin (OCIL), is a type II transmembrane C-type lectin receptor primarily expressed upon immune cell activation in T cells, B cells, NK cells, and plasmacytoid and monocyte-derived dendritic cells. CLEC2D interacts with NKR-P1A (KLRB1, CD161) on NK cells and some subsets of T cells, inhibiting NK cell cytotoxicity while alternatively inducing proliferation and IFNγ production in T cells. CLEC2D is also expressed by osteoblasts, inhibiting osteoclast formation and bone resorption. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of U87-MG, Saos2. The target is localized to the endoplasmic reticulum, cell membrane.
Product Name:
Recombinant CLEC2D Monoclonal Antibody
SKU:
AGEL6896
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
C type lectin related f, C type lectin superfamily 2, C-type lectin domain family 2 member D, CLAX, CLC2D, CLEC2D, CLEC2D protein, Clec2d5, L LT1, Lectin like NK cell receptor, Lectin like transcript 1, Lectin-like NK cell receptor, Lectin-like transcript 1, LLT, LLT-1, LLT1, member D, OCIL, Osteoclast inhibitory lectin
Reactivity:
Human
Immunogen:
Recombinant human CLEC2D fragment
Applications:
WB
Clonality:
Recombinant Monoclonal
Clone No:
C331591
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
CLEC2D
Conjugation:
Unconjugated
Observed MW:
25-35 kDa
Calculated MW:
22 kDa
Recommended Dilution:
WB 1:500-1000
UniProt:
Q9UHP7
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
