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Key Features

Recombinant CPS1 Monoclonal Antibody (AGEL6832)

Datasheet MSDS
SKU AGEL6832
Product Type Antibody
Reactivity Human, Rat, Mouse
Applications WB, IHC
Host Species Rabbit
Clonality Monoclonal
Clone C121527
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant CPS1 Monoclonal Antibody

The Recombinant CPS1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C121527) against CPS1. Carbamoyl phosphate synthetase 1 (CPS1), a rate-limiting enzyme in the urea cycle, catalyzes the conversion of ammonia and bicarbonate to carbamoyl phosphate in mitochondria. Non-small cell lung carcinoma (NSCLC) cells with oncogenic KRAS and loss of the tumor suppressor LKB1 express CPS1 and depend on this enzyme for growth. CPS1 maintains pyrimidine/purine balance in these cancer cells. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of HeLa, Human liver, Mouse liver, Rat liver and IHC analysis of Human hepatocellular carcinoma, Human liver, Mouse small intestine, Rat liver. The target is localized to the mitochondrion.

Product Name:Recombinant CPS1 Monoclonal Antibody
SKU:AGEL6832
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:Carbamoyl phosphate synthase, Carbamoyl phosphate synthase [ammonia], Carbamoyl phosphate synthase [ammonia] mitochondrial, Carbamoyl phosphate synthetase 1, Carbamoyl phosphate synthetase 1 mitochondrial, Carbamoyl phosphate synthetase I, carbamoyl-phosphate synthase, carbamoyl-phosphate synthase 1, Carbamoyl-phosphate synthase [ammonia], Carbamoyl-phosphate synthetase I, Carbamoylphosphate synthase, Carbamoylphosphate synthetase 1, Carbamoylphosphate synthetase I, CPS, CPS 1, CPS1, CPSASE, CPSase 1, CPSase I, CPSASE1, CPSM, mitochondrial, MS738, PHN
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant human CPS1 fragment
Applications:WBIHC
Clonality:Recombinant Monoclonal
Clone No:C121527
Host:Rabbit
Isotype:Rabbit IgG
Target:CPS1
Conjugation:Unconjugated
Observed MW:165 kDa
Calculated MW:165 kDa
Recommended Dilution:WB 1:1000-5000; IHC 1:50-100
UniProt:P31327
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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