The Recombinant CRMP2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111360) against CRMP2. Collapsing response mediator protein 2 (CRMP2 and DPYSL2) is known to be a member of the CRMP family. CRMP2 reportedly functions to regulate synaptic transmission, control MT dynamics, and modulate vesicle trafficking in cells and the developing brain. Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC and IF applications. It has been validated by WB analysis of SHSY-5Y, NIH-3T3, Mouse brain, Rat brain, IHC analysis of Human colon cancer and IF analysis of HCT116, NIH3T3. The target is localized to the cell cytosol and membrane.