Description
Recombinant Cyclooxygenase 2 Monoclonal Antibody
The Recombinant Cyclooxygenase 2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C123250) against Cyclooxygenase 2. Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB and IHC-P applications. It has been validated by WB analysis of Rat Rat Brain and IHC analysis of Human lung cancer. The target is localized to the Microsome membrane. Endoplasmic reticulum membrane.
| Product Name: | Recombinant Cyclooxygenase 2 Monoclonal Antibody |
| SKU: | AGEL8555 |
| Size: | 50 µL, 100 µL |
| Antibody Type: | Recombinant Monoclonal Antibody |
| Synonyms: | COX 2, COX-2, COX2, Cyclooxygenase, Cyclooxygenase 2, Cyclooxygenase 2b, Cyclooxygenase-2, Cyclooxygenase2, EC 1.14.99.1, fj02a10, Glucocorticoid-regulated inflammatory cyclooxygenase, Glucocorticoid-regulated inflammatory Prostaglandin G/H synthase, GRIPGHS, hCox 2, M, Macrophage activation-associated marker protein P71/73, OTTHUMP00000033524, PES-2, PGG/HS, PGH synthase 2, PGH2, PGHS 2, PGHS-2, PGHS2, PHS 2, PHS II, PHS2, Prostaglandin endoperoxide synthase 2, Prostaglandin endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), Prostaglandin G/H synthase, Prostaglandin G/H synthase 2, Prostaglandin G/H synthase 2 precursor, Prostaglandin G/H synthase and cyclooxygenase, Prostaglandin H2 synthase 2, Prostaglandin-endoperoxide synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase), PTGS2, ptgs2a, TIS10, TIS10 protein, unp1239, wu:fj02a10 |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | A synthetic peptide of human COX2 |
| Applications: | WBIHC-P |
| Clonality: | Recombinant Monoclonal |
| Clone No: | C123250 |
| Host: | Rabbit |
| Isotype: | Rabbit IgG |
| Target: | Cyclooxygenase 2 |
| Conjugation: | Unconjugated |
| Observed MW: | 69 kDa |
| Calculated MW: | 69 kDa |
| Recommended Dilution: | WB 1:500-1000; IHC 1:50-100 |
| UniProt: | P35354 |
| Purification: | Affinity purification |
| Concentration: | 0.3 mg/mL |
| Buffer: | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein. |
| Storage: | Store at -20°C valid for 12 months. Avoid freeze / thaw cycles. |