The Recombinant E2F1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C113339) against E2F1. The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC-P and IF applications. It has been validated by WB analysis of C6, 3T3 and IF analysis of Human tonsil, Hela. The target is localized to the nucleus.