The Recombinant Eg5 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C173290) against Eg5. This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB and IF applications. It has been validated by WB analysis of Hela, A549, HL-60, U2OS, C6 and IHC analysis of Hela. The target is localized to the Cytoplasm. Cytoplasm>cytoskeleton>spindle pole.