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Recombinant EIF2S1 Monoclonal Antibody (AGEL6441)

Datasheet MSDS
SKU AGEL6441
Product Type Antibody
Reactivity Human, Rat, Mouse
Applications WB, IHC, IF, ELISA
Host Species Rabbit
Clonality Monoclonal
Clone C111135
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant EIF2S1 Monoclonal Antibody

The Recombinant EIF2S1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C111135) against EIF2S1. The eukaryotic translation initiation factor 2-α subunit (EIF2S1) is the first regulatory step that catalyzes the initiation of protein synthesis and promotes the binding of the initial tRNA to the 40S ribosomal subunit. As an important translation initiation factor, the eukaryotic initiation factor 2-α subunit is regulated by a variety of signal molecules, that is, it functions by regulating the phosphorylation and acetylation status of EIF2S1. Kinases activated by viral infection (PKR), endoplasmic reticulum stress (PERK/PEK), amino acid deprivation (GCN2) or heme deficiency (HRI) can phosphorylate EIF2S1 to regulate the transcription and translation of cell-related genes and enhance Cell protection mechanism. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by WB analysis of K562, NIH-3T3, PC-12 and IHC analysis of Rat brain. The target is localized to the cytoplasm.

Product Name:Recombinant EIF2S1 Monoclonal Antibody
SKU:AGEL6441
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:EIF, EIF 2, EIF 2 alpha, EIF 2A, EIF 2alpha, EIF-2, eIF-2-alpha, EIF-2A, EIF-2alpha, EIF2, EIF2 alpha, EIF2A, EIF2S, EIF2S1, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 1 alpha, Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa, Eukaryotic translation initiation factor 2 subunit alpha, IF2A
Reactivity:Human, Mouse, Rat
Immunogen:The specific immunogen used to produce this antibody is proprietary information.
Applications:WBIHCIFELISA
Clonality:Recombinant Monoclonal
Clone No:C111135
Host:Rabbit
Isotype:Rabbit IgG
Target:EIF2S1
Conjugation:Unconjugated
Observed MW:65 kDa
Calculated MW:65 kDa
Recommended Dilution:WB 1:2000-10000; IHC 1:200-500; IF 1:200-1000; ELISA 1:5000-20000
UniProt:Q9BY44, Q8BJW6
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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