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Key Features

Recombinant FAK Monoclonal Antibody (AGEL8559)

Datasheet MSDS
SKU AGEL8559
Product Type Antibody
Reactivity Human, Mouse, Rat
Applications WB, IHC-P
Host Species Rabbit
Clonality Monoclonal
Clone C123254
Conjugate Unconjugated
$461 - $632

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Description

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Recombinant FAK Monoclonal Antibody

The Recombinant FAK Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C123254) against FAK. FAK (Focal adhesion kinase 1) is also named as FAK1, FADK, pp125FAK, FAK and belongs to the protein kinase superfamily. It is a critical tyrosine kinase that modulates cell adhesion, migration, proliferation and survival in response to extracellular signals. It also acts as a pivotal signal 'integrator', controlling and coordinating cellular responses that include cell migration, survival, proliferation and, epithelial tissue repair after DNA damage. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB and IHC-P applications. It has been validated by WB analysis of K562, C6, 3T3, Hela and IHC analysis of Human colon cancer. The target is localized to the Cell junction>focal adhesion. Cell membrane. Constituent of focal adhesions.

Product Name:Recombinant FAK Monoclonal Antibody
SKU:AGEL8559
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:FADK, FADK 1, FAK related non kinase polypeptide, FAK1, Focal adhesion Kinase, Focal adhesion kinase 1, Focal adhesion kinase isoform FAK Del33, Focal adhesion kinase related nonkinase, FRNK, p125FAK, pp125FAK, PPP1R71, Protein phosphatase 1 regulatory subunit 7, Protein phosphatase 1 regulatory subunit 71, Protein tyrosine kinase 2, Protein-tyrosine kinase 2, Ptk2, PTK2 protein tyrosine kinase 2
Reactivity:Human, Mouse, Rat
Immunogen:A synthetic peptide of human FAK
Applications:WBIHC-P
Clonality:Recombinant Monoclonal
Clone No:C123254
Host:Rabbit
Isotype:Rabbit IgG
Target:FAK
Conjugation:Unconjugated
Observed MW:125 kDa
Calculated MW:119 kDa
Recommended Dilution:WB 1:1000-2000; IHC 1:50-100
UniProt:Q05397
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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