The Recombinant FEN1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C721543) against FEN1. Flap endonuclease-1 (FEN-1) is a structure-specific nuclease with multiple functions in DNA processing pathways. The replication and DNA repair activities of FEN-1 are critical for genomic stability in the eukaryotic cell. Through interaction with proliferation cell nuclear antigen (PCNA), FEN-1 helps coordinate Okazaki fragment maturation by removing RNA-DNA primers. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human and Rat samples.
This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of HeLa, HepG2, Jurkat, C6 and IHC analysis of Human tonsil, Human ovarian cancer, Human testis. The target is localized to the mitochondrion, nucleus.
Product Name:
Recombinant FEN1 Monoclonal Antibody
SKU:
AGEL6848
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
FEN, FEN-1, FEN1, MF1, RAD, RAD2
Reactivity:
Human, Rat
Immunogen:
Recombinant human FEN1 fragment
Applications:
WBIHC
Clonality:
Recombinant Monoclonal
Clone No:
C721543
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
FEN1
Conjugation:
Unconjugated
Observed MW:
43 kDa
Calculated MW:
43 kDa
Recommended Dilution:
WB 1:1000; IHC 1:200-500
UniProt:
P39748
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.