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Key Features

Recombinant FOXL2 Monoclonal Antibody (AGEL6455)

Datasheet MSDS
SKU AGEL6455
Product Type Antibody
Reactivity Human, Rat, Mouse
Applications WB, IHC
Host Species Rabbit
Clonality Monoclonal
Clone C121149
Conjugate Unconjugated
$606 - $843

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Description

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Recombinant FOXL2 Monoclonal Antibody

The Recombinant FOXL2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C121149) against FOXL2. Winged helix forkhead transcription factor 2 (FOXL2) promotes the proliferation and differentiation of granulosa cells by regulating the transcription of target genes, which is a key factor for ovarian differentiation and function maintenance. FOXL2 repels SOX9, Sertoli cells inhibit the transcription of SOX9 gene to prevent the transdifferentiation of the ovary to the testis; FOXL2 can also participate in the physiological regulation of endometrial tissue. Mutation of FOXL2 can cause small eyelid syndrome (BPES) and premature ovarian failure, so FOXL2 can be used as an important indicator of the prognosis and tumor progression of ovarian granulosa cell tumor, and it is also a specific marker of ovarian sex cord stromal tumor (SCST). Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.

This antibody is suitable for WB and IHC applications. It has been validated by WB analysis of Mouse ovary, Rat ovary and IHC analysis of Human ovarian granulosa cell tumor, Mouse ovary, Rat ovary(Negative tissue). The target is localized to the nucleus.

Product Name:Recombinant FOXL2 Monoclonal Antibody
SKU:AGEL6455
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:FOXL, Foxl2, Pfrk
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant human FOXL2 fragment
Applications:WBIHC
Clonality:Recombinant Monoclonal
Clone No:C121149
Host:Rabbit
Isotype:Rabbit IgG
Target:FOXL2
Conjugation:Unconjugated
Observed MW:50 kDa
Calculated MW:38 kDa
Recommended Dilution:WB 1:1000; IHC 1:100-1000
UniProt:O88470
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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