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Key Features

Recombinant FTO Monoclonal Antibody (AGEL8561)

Datasheet MSDS
SKU AGEL8561
Product Type Antibody
Reactivity Human
Applications WB, IHC-P, IF
Host Species Rabbit
Clonality Monoclonal
Clone C313256
Conjugate Unconjugated
$461 - $632

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Description

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Recombinant FTO Monoclonal Antibody

The Recombinant FTO Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C313256) against FTO. This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. Produced by recombinant technology in Rabbit hosts and purified by affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB, IHC-P and IF applications. It has been validated by WB analysis of Hela, Jurkat and IF analysis of Human lung cancer, Hela. The target is localized to the nucleus.

Product Name:Recombinant FTO Monoclonal Antibody
SKU:AGEL8561
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:AlkB homolog 9, ALKBH9, Alpha-ketoglutarate-dependent dioxygenase FTO, AW743446, Fat mass and obesity-associated protein, FATSO, FTO, GDFD, HOMOLOG OF, KIAA1752, mKIAA1752, MOUSE, Protein fatso
Reactivity:Human
Immunogen:A synthetic peptide of human FTO
Applications:WBIHC-PIF
Clonality:Recombinant Monoclonal
Clone No:C313256
Host:Rabbit
Isotype:Rabbit IgG
Target:FTO
Conjugation:Unconjugated
Observed MW:58 kDa
Calculated MW:58 kDa
Recommended Dilution:WB 1:2000-5000; IHC 1:50-100; IF 1:20-100
UniProt:Q9C0B1
Purification:Affinity purification
Concentration:0.3 mg/mL
Buffer:50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% stabilizer and 0.05% protective protein.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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