The Recombinant Gemin 2 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C131375) against Gemin 2. Gem-associated protein 2 (Gemin 2), also called survival of motor neuron protein-interacting protein 1 (SIP1), is a protein that in humans is encoded by the GEMIN2 gene. Gemin 2 has been shown to interact with DDX20 and SMN1. The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB applications. It has been validated by WB analysis of HepG2, U-2 OS, F9, Rat testis. The target is localized to the cytoplasm, nucleus.
Product Name:
Recombinant Gemin 2 Monoclonal Antibody
SKU:
AGEL6680
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
Component of gems 2, Gem (nuclear organelle) associated protein 2, Gem associated protein 2, GEMI2, GEMIN, Gemin-2, GEMIN2, SIP, SIP 1, SIP-1, SIP1, SIP1 delta, SIP1-delta, SMN interacting protein 1, SMN interacting protein 1 delta, SMN-interacting protein 1, Survival interacting protein 1, Survival of motor neuron protein interacting protein 1, Survival of motor neuron protein-interacting protein 1
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant human Gemin 2 fragment
Applications:
WB
Clonality:
Recombinant Monoclonal
Clone No:
C131375
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
Gemin 2
Conjugation:
Unconjugated
Observed MW:
32 kDa
Calculated MW:
32 kDa
Recommended Dilution:
WB 1:500-1000
UniProt:
O14893
Purification:
Protein A
Concentration:
1 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.