Description
Recombinant HER2/ErbB2/CD340 Monoclonal Antibody
The Recombinant HER2/ErbB2/CD340 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110006) against ERBB2. This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC-P, ICC/IF, FC and IP applications. It has been validated by WB analysis of HeLa, A549, A431 and IHC analysis of Human breast cancer. The target is localized to the cell membrane.
| Product Name: | Recombinant HER2/ErbB2/CD340 Monoclonal Antibody |
| SKU: | AGEL5325 |
| Size: | 50 µL, 100 µL |
| Antibody Type: | Recombinant Monoclonal Antibody |
| Synonyms: | C erb B2/neu protein, CD340, CD340 antigen, Cerb B2/neu protein, CerbB2, ENV, ENVW, Erb b2 receptor tyrosine kinase 2, erb-B2, erb-b2 receptor tyrosine kinase, erb-b2 receptor tyrosine kinase 2, ERBB, ERBB2, ERVWE1, HER, HER 2, HER 2/NEU, HER-2, HER-2/neu, HER2, HER2/ErbB, HER2/ErbB2, Herstatin, HERV-7q, HERV-W-ENV, HERV7Q, HERVW, HERVWENV, Human epidermal growth factor receptor 2, Metastatic lymph node gene 19 protein, MLN, MLN 19, MLN19, NEU, NEU proto oncogene, neuro/glioblastoma derived oncogene homolog, neuro/glioblastoma derived oncogene homolog (avian), Neuroblastoma/glioblastoma derived oncogene homolog, NGL, p185, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, Receptor tyrosine-protein kinase erbB, Receptor tyrosine-protein kinase erbB-2, TKR, TKR1, Tyrosine kinase type cell surface receptor HER2, Tyrosine kinase-type cell surface receptor HER, Tyrosine kinase-type cell surface receptor HER2, V erb b2 avian erythroblastic leukemia viral oncogene homolog 2, V erb b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog), V erb b2 avian erythroblastic leukemia viral oncoprotein 2, V erb b2 erythroblastic leukemia viral oncogene homolog 2, Verb b2 erythroblastic leukemia viral oncogene homolog 2 |
| Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant Human HER2/ErbB2/CD340 Protein |
| Applications: | WBIHC-PICC/IFFCIP |
| Clonality: | Recombinant Monoclonal |
| Clone No: | C110006 |
| Host: | Rabbit |
| Isotype: | Rabbit IgG |
| Target: | ERBB2 |
| Conjugation: | Unconjugated |
| Observed MW: | 185 kDa |
| Calculated MW: | 138 kDa |
| Recommended Dilution: | WB 1:1000; IHC-P: 1:500-2000; ICC/IF: 1:100-200; FC: 1:50-100; IP: 1:20-50 |
| UniProt: | P04626 |
| Purification: | Protein A |
| Concentration: | 1 mg/mL |
| Buffer: | 0.2 µm filtered solution in PBS |
| Storage: | Store at -20°C valid for 12 months. Avoid freeze / thaw cycles. |
