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Recombinant HSD17B1 Monoclonal Antibody (AGEL6773)

Datasheet MSDS
SKU AGEL6773
Product Type Antibody
Reactivity Human
Applications WB, IHC-P, FC, IP
Host Species Rabbit
Clonality Monoclonal
Clone C321468
Conjugate Unconjugated
$606 - $843

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Description

system_update_altDatasheetsystem_update_altMSDS

Recombinant HSD17B1 Monoclonal Antibody

The Recombinant HSD17B1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C321468) against HSD17B1. HSD17B1 is a member of the 17beta-hydroxysteroid dehydrogenase family of short-chain dehydrogenases/reductases. It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues. HSD17B1 catalyzes the last step in estrogen activation, using NADPH to convert estrogens E1 and E2 and androgens like 4-androstenedione, to testosterone. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.

This antibody is suitable for WB, IHC-P, FC and IP applications. It has been validated by WB analysis of Human placenta. The target is localized to the cytoplasm.

Product Name:Recombinant HSD17B1 Monoclonal Antibody
SKU:AGEL6773
Size:50 µL, 100 µL
Antibody Type:Recombinant Monoclonal Antibody
Synonyms:17 beta HSD 1, 17 beta hydroxysteroid dehydrogenase type 1, 17-beta-HSD, 17-beta-HSD 1, 17-beta-hydroxysteroid dehydrogenase type 1, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, DHB1, E17KSR, E2DH, EDH17B1, EDH17B2, EDHB, EDHB17, Estradiol 17 beta dehydrogenase 1, Estradiol 17-beta-dehydrogenase 1, HSD, HSD17, HSD17B, HSD17B1, Hydroxysteroid (17 beta) dehydrogenase 1, member 1, MGC13814, Placental 17 beta hydroxysteroid dehydrogenase, Placental 17-beta-hydroxysteroid dehydrogenase, SDR28C, SDR28C1, Short chain dehydrogenase/reductase family 28CE
Reactivity:Human
Immunogen:A synthetic peptide of human HSD17B1
Applications:WBIHC-PFCIP
Clonality:Recombinant Monoclonal
Clone No:C321468
Host:Rabbit
Isotype:Rabbit IgG
Target:HSD17B1
Conjugation:Unconjugated
Observed MW:35 kDa
Calculated MW:35 kDa
Recommended Dilution:WB 1:2000-20000; IHC-P 1:100-200; IP 1:50; FCM 1:100-200
UniProt:P14061
Purification:Protein A
Concentration:1 mg/mL
Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
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