Aspartoacylase 3, also known as ACY3, N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming), Acylase III, Aminoacylase-3, Aspartoacylase-2, Aspartoacylase-2, HCV core-binding protein 1 and ASPA2, is a member of the Aspartoacylase subfamily. ACY3 plays an important role in deacetylating mercapturic acids in kidney proximal tubules and acts on N-acetyl-aromatic amino acids.ACY3 is located in the cytoplasm of S2 and S3 proximal tubules and the apical domain of S1 proximal tubules. ACY3 protein is also expressed at low levels in stomach, testis, heart, brain, lung and liver, and may function as an HCV (Hepatitis C virus) core binding protein.
Product Name:
Human ACY3 Recombinant Protein (RPES5145)
Product Code:
RPES5145
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming),ACY3,Acylase III,Aminoacylase-3,ACY-3,Aspartoacylase-2,Hepatitis C virus core-binding protein 1,HCBP1,HCV core-binding protein 1,ASPA2,ACY3
Accession:
Q96HD9
Sequence:
Met 1-Ser319
Fusion tag:
N-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human N-acyl-aromatic-L-amino acid amidohydrolase is produced by our E.coli expression system and the target gene encoding Met1-Ser319 is expressed with a 6His tag at the N-terminus.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
37.4 kDa
AP Mol Mass:
35 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM Tris,100mM NaCl,1mM DTT,10%Glycerol,pH 8.0.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
