Recombinant Human ACY3 Protein (His Tag) (RPES5145)

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SKU:
RPES5145
€303

Description

ELISA Kit Technical Manual

Recombinant Human ACY3 Protein (His Tag)

Background:Aspartoacylase 3, also known as ACY3, N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming), Acylase III, Aminoacylase-3, Aspartoacylase-2, Aspartoacylase-2, HCV core-binding protein 1 and ASPA2, is a member of the Aspartoacylase subfamily. ACY3 plays an important role in deacetylating mercapturic acids in kidney proximal tubules and acts on N-acetyl-aromatic amino acids.ACY3 is located in the cytoplasm of S2 and S3 proximal tubules and the apical domain of S1 proximal tubules. ACY3 protein is also expressed at low levels in stomach, testis, heart, brain, lung and liver, and may function as an HCV (Hepatitis C virus) core binding protein.
Name:Recombinant Human ACY3 Protein (His Tag)
Size:10µg
Assay Genie SKU:RPES5145
Synonyms:N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming);ACY3;Acylase III;Aminoacylase-3;ACY-3;Aspartoacylase-2;Hepatitis C virus core-binding protein 1;HCBP1;HCV core-binding protein 1;ASPA2;ACY3
Species:Human
Expression host:E.coli
Sequence:Met 1-Ser319
Accession:Q96HD9
Mol Mass:37.4 kDa
AP Mol Mass:35 kDa
Tag:N-6His
Purity:> 90 % as determined by reducing SDS-PAGE.
Endotoxin:< 1.0 EU per µg as determined by the LAL method.
Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Formulation:Supplied as a 0.2 um filtered solution of 20mM Tris,100mM NaCl,1mM DTT,10%Glycerol,pH 8.0.
Reconstitution:Please refer to the printed manual for detailed information.
UniProt Protein Function:ACY3: Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Belongs to the AspA/AstE family. Aspartoacylase subfamily.
UniProt Protein Details:

Protein type:Amino Acid Metabolism - alanine, aspartate and glutamate; Hydrolase; EC 3.5.1.114; Amino Acid Metabolism - histidine

Chromosomal Location of Human Ortholog: 11q13.2

Cellular Component: cytosol

Molecular Function:aminoacylase activity; protein binding

Biological Process: xenobiotic metabolic process

UniProt Code:Q96HD9
NCBI GenInfo Identifier:34395507
NCBI Gene ID:91703
NCBI Accession:Q96HD9.1
UniProt Related Accession:Q96HD9
Molecular Weight:35,241 Da
NCBI Full Name:N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)
NCBI Synonym Full Names:aminoacylase 3
NCBI Official Symbol:ACY3  
NCBI Official Synonym Symbols:ACY-3; HCBP1  
NCBI Protein Information:N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)
UniProt Protein Name:N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)
UniProt Synonym Protein Names:Acylase III; Aminoacylase-3; ACY-3; Aspartoacylase-2; Hepatitis C virus core-binding protein 1; HCBP1; HCV core-binding protein 1
Protein Family:N-acyl-aromatic-L-amino acid amidohydrolase
UniProt Gene Name:ACY3  
UniProt Entry Name:ACY3_HUMAN
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Additional Information

Product type:
Recombinant Protein
Host species:
E.coli
Reactivity:
Human
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