Blog
Syngeneic Mouse Models & Checkpoint Inhibitors
Syngenic Mouse Models & Immune Checkpoint Inhibitors
A quick guide t
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25th Jan 2023
Apoptosis (Intrinsic & Extrinsic Pathways)
A Guide to Apoptosis
At Assay Genie we have created a comprehensive guid
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2nd Dec 2022
B Cell Types, Antigen Recognition & Activation
B Cell Types, Antigen Recognition & Activation
A comprehensive guide to B cells!
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21st Nov 2022
Flow Cytometry Protocol | 10 Hints & Tips
Flow Cytometry Protocol
The meaning is in the name:
Flow = in motion, Cyto = cells, Metry = measure.
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7th Nov 2022
Cortisol and the Immune Response
What is Cortisol?
Cortisol is a steroid hormone, classified as a member of the glucocorticoid family of hormones. Cortisol is i
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26th Oct 2022
Cell Synchronisation Methods
What is Cell Synchronisation?
Cell synchronisation is a process by which cells at different stages of the cell cycle in a culture are brought to the sa
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26th Oct 2022
What is RNAi? All You Need to Know
RNA interference (RNAi), also referred to as Post-Transcriptional Gene Silencing (PTGS), is the process by which RNA molecules silence genes in response to double-stranded RNA. This
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4th Aug 2022
Cancer Metabolism: Tumorigenesis, Metabolic Therapy & The Warburg Effect
Cancer Metabolism is the mechanism by which cancer cells make energy in order for them to grow and spread. Even in the presence of oxygen, cancer cells increase glucose uptake and produce
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4th Aug 2022
A Quick Guide to Myelin
The myelin sheath is an insulating layer around nerve cells. It is made up of a substance called myelin, which is produced by special cells called oligodendrocytes. Myelin protects the ner
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4th Aug 2022
An Insight Into Necrosis- Causative Effects And Methods Of Prevention
Necrosis is the death of cells or tissue due to loss of blood flow. This can happen when blood vessels are damaged or blocked, preventing oxygen and nutrients from reaching the tissue. Necr
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4th Aug 2022
A Quick Guide To Mycoprotein
Mycoprotein is an alternative source of protein that can be used in place of meat. It is made from a fungi called Fusarium venenatum, and is consumed by vegetarians and vegans as a meat sub
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4th Aug 2022
Cytokine Storms: What happens when the immune system overreacts?
This article describes an account of a hyper activated immune response known as a cytokine storm. It contains infections and diseases implicated in cytokine storms such as SARS-CoV-
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1st Aug 2022
Gut Inflammation and Inflammatory Diseases
This article contains an account of gut inflammation, describing methods in which the gut may become inflamed, markers of inflammation and inflammatory diseases. In addition, it des
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1st Aug 2022
The Role of Tumor Suppressor Genes in Cancer: Knudson Hypothesis & Oncogenes
The focus of this article is Tumor Suppressor Genes. There are various different types of tumor suppressor genes, with BRCA being one of the most popular. The role of Tumor Suppressor Gene
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27th Jul 2022
The p53 Protein: Mutations, Cancer & Cell Signalling
This article contains an overview of the p53 protein, including its function and signalling pathway. It also looks at p53 protein domains, p53 target genes and the relationship betw
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26th Jul 2022
Guide to Fluorescence Activated Cell Sorting (FACs): The Latest Technology in Cell Separation
Fluorescence activated cell sorting (FACS) is a cutting-edge technique used to isolate individual cells from a sample and analyse their properties. In this guide, we
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26th Jul 2022
Monoclonal Vs Polyclonal antibodies: Key features
This article describes monoclonal and polyclonal antibodies, highlighting similarities and key differences. It further explores the applications of antibodies from research to pharma in di
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20th Jul 2022
The Role of Zonulin In Intestinal Permeability
This article provides an overview of the protein Zonulin (function, structure, location). It describes tight junction proteins, leaky gut and Zonulin-related diseases. This includes celiac
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20th Jul 2022
An Overview of the glycoprotein GM-CSF
This article breaks down the glycoprotein Granulocyte-macrophage colony-stimulating factor (GM-CSF) detailing its structure, function and therapeutic uses. It also describes its role in im
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20th Jul 2022
Oct-4 Stem Cells & Stem Cell Differentiation
This article provides information surrounding Stem cells, with particular focus on Oct-4 Stem Cells. Additionally, stem cell pluripotency, stem cell differentiation and the potential of st
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20th Jul 2022
A Guide To Tau Proteins & Tauopathies
This article contains an overview of protein Tau mentioning its structure, function and modifications (mutation, phosphorylation). Neurodegenerative diseases, termed Tauopathies, are discu
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20th Jul 2022
CV writing tips for scientists
Making the switch!
This article provides some help on CV writing tips for scientists for PhDs and PostDocs looking for jobs outside of academ
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24th May 2022
CXCL16 – Review
CXCL16/SR-POX gene has five exons, spans 6283 bp and is found on chromosome 17, position 17p13.2 (Huang et al., 2010) (genecards). CXCL16, also known as SR-PSOX, is a multi-functiona
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24th May 2022
Promising COVID-19 Therapeutics
SARS-CoV-2, the causative viral agent of the novel coronavirus disease COVID-19, has sparked a global effort for creating prophylactic and therapeutic interventions. The following
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23rd May 2022