Blog
NLRP3 Inflammasome & Cytokine Secretion
Nod-like receptors
Nod like receptors (NLRs) are a versatile family of relatively recently discovered intracellular receptors which have a broad range of funct
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23rd May 2022
COVID-19 Workplace Testing
Workplace Testing for COVID-19
Corporate Testing for COVID-19
The impact of COVID-19 on the economy has been staggering. Current
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23rd May 2022
COVID-19 Antibody Testing
COVID-19 Antibody Testing
Antibody Production in COVID-19
COVID-19, the novel coronavirus disease caused by SARS-CoV-2, can be d
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23rd May 2022
Antibody Seroconversion Response in COVID-19
Seroconversion Implications in SARS-CoV-2 Diagnostic Testing
Key Points:
COVID-19, the pandemic coronavirus disease caused by
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23rd May 2022
COVID-19 Vaccine Candidates
What is COVID-19
COVID-19, the disease caused by the coronavirus named SARS-CoV-2, first identified in Wuhan, China in December 2019 has spread globally, resul
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23rd May 2022
EGF Family
Epidermal Growth Factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor epidermal growth factor receptor (EGFR) which triggers ligand-induced d
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23rd May 2022
Promising COVID-19 Therapeutics
SARS-CoV-2, the causative viral agent of the novel coronavirus disease COVID-19, has sparked a global effort for creating prophylactic and therapeutic interventions. The following five com
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23rd May 2022
B Cell Types, Antigen Recognition & Activation
What is a B Cell?
Most of our immune system is dependent on the huge diversity of immunoglobulin receptors called antibodies which have the ability to bind to
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23rd May 2022
Research Universities in Ireland
Since I am from Ireland I thought I would give as comprehensive view as possible for Research Universities in Ireland. By now you are probably considering looking for a PhD or PostDoc posit
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20th May 2022
Top 10 Universities in the UK
Before I even started my PhD I was already thinking about carrying out PostDoc in a foreign country and had my sights set on going to the US. I had previously carried out a degree in Genetics
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20th May 2022
Dendritic Cells - Markers, Activation & Subtypes
What is a Dendritic Cell?
Dendritic cells (DCs) are a type of immune cell that acts as a messenger between the innate and adaptive immune system. They are prof
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9th May 2022
Tips for writer’s block
Writer’s block can be a big stumbling block when trying to write your PhD thesis, grant or a paper you are trying to get publish. During the early stages of writing my PhD thes
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5th May 2022
29 PhD thesis writing tips
PhD thesis length
A PhD thesis is a long and detailed piece of academic writing that requires significant amounts of research and careful planning. Depending
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2nd May 2022
Spindle Assembly Checkpoint review
Spindle assembly checkpoint
The spindle assembly checkpoint (SAC), or mitotic checkpoint, is the main cell cycle control mechanism that governs mitosis. Incorrec
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26th Apr 2022
Interleukin-8 signalling
IL-8 Overview
Interleukin-8 (IL-8), also known as CXCL8, was discovered over 30 years ago as a small molecule that could promote chemotaxis
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26th Apr 2022
Apoptosis (Intrinsic & Extrinsic Pathways)
Apoptosis definition
Apoptosis, from the Greek meaning falling off, was introduced as a concept in its modern sense by Kerr in 1972 (Kerr et
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22nd Apr 2022
How do different types of vaccines work?
What is a vaccine?
A vaccine is a pharmacological product that gives the recieving patient's immune system a chance to learn how to fight infection with decreased risk of illness. Vaccination
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21st Apr 2022
Macrophage, M1 & M2, Polarization and Function
What is a Macrophage?
Macrophages are a type of white blood cell of the immune system that engulfs and digests cellular debris, foreign substances, pathogens a
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14th Apr 2022
NK Cells, Markers & Function
What are NK Cells?
Natural Killer (NK) cells were first described in the mid-1970’s as a population of innate lymphocytes that were able to mediate cytot
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13th Apr 2022
T Cell types, activation, polarization, & function
Helper T Cells
Cytotoxic T Cells
Regulatory T Cells
CAR-T Cells
T Cell Development
T Cell Cytokine Signalling
T Cell Exhaustion
T Cell Ant
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12th Apr 2022
What is pharmacogenomics?
What is pharmacogenomics
Pharmacogenomics is how DNA variation and drugs interact and how this can optimise patient health; this involves studying pharmacokinetics and pharmacodynamics. Pharm
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10th Apr 2022
Novel Gene Therapy for Cystic Fibrosis
Novel Gene Therapies for Cystic Fibrosis
Cystic Fibrosis
Cystic fibrosis (CF) is an autosomal recessive, life-limiting disease resulting from gene mutations that encode the cystic fibrosis tr
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6th Apr 2022
Ovarian Cancer: Symptoms, Causes, Diagnosis and Treatment
Ovarian cancer is the fourth most common cancer in women. Ovarian cancer is when the normal cells in the ovary change and grow to form a tumour. Because the ovaries are located deep within
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3rd Apr 2022
Chronic myelogenous leukaemia (CML) – Review
Chronic myelogenous leukaemia (CML) is a myeloproliferative haematopoietic malignancy, characterised by a karyotypic abnormality present in more than 95% of cases known as the Philadelphia ch
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1st Apr 2022