Blog
Psychiatric disorders and lipocalin
Ana Catarina Ferreira
Psychiatric disorders, including anxiety and depression, are highly prevalent conditions and its incidence is expected to increase as i
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11th Mar 2021
A mechanopharmacology approach to overcome chemoresistance in pancreatic cancer
Mechanical forces are common in biological systems and dominate numerous perturbations that are relevant to human physiology and disease. Mechanobiology is a new field that evaluates the eff
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11th Mar 2021
Pancreatic Cancer and its Poor Prognosis
Myrna Hurtado, PhD Student, University of North Texas Health Science Center
Advancements in modern medicine have resulted in significantly prolonging and a
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11th Mar 2021
Autophagy alterations in Alzheimer’s disease
By Diana-Madalina Stan, PhD student, University of Salford
Disease Description
Alzheimer’s disease (AD), the most common cause of dementia, is
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11th Mar 2021
Cytokinesis review
By John Bannon PhD
Early Cytokinesis
Early cytokinesis; from anaphase to midbody formation cytokinesis is the physical s
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11th Mar 2021
Diabetic Retinopathy: premature cellular senescence and microvascular dysfunction
By Pietro Maria Bertelli, PhD Candidate, Queens University Belfast
Introduction
Eye complications are very frequent in patients with diabetes, an
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11th Mar 2021
Psychiatric disorders & LCN2
By Ana Catarina Ferreira, PhD Candidate, Univeristy of Minho, Portugal
Psychiatric disorders, including anxiety and depression, are highly prevalent con
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11th Mar 2021
From Stem Cells To Neurons: A Cnidarian Approach
By Eleni Chrysostomou, PhD Candidate, NUIG
Why do we need to know how the Nervous System develops and regenerates?
The structure and function of
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11th Mar 2021
COVID-19 Biomarkers
SARS-CoV-2 Background
COVID-19 is characterised by a series of biological markers. In some instances, these biomarkers can be used as potenti
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10th Mar 2021
A broccoli juice a day keep the heart attack away
Alex Lloyd PhD Candidate, Dublin Institute of Technology
Did you know that roughly 17.5 million people worldwide die annually from Cardiovascular diseases
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10th Mar 2021
Tocilizumab (Actemra®) in COVID-19 Treatment
Tocilizumab (Actemra®) in COVID-19 Treatment
What is Tocilizumab?
Tocilizumab, also called atlizumab, is an immunosuppress
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10th Mar 2021
Do you know…migraines affect more than 10% of the world population?
By Francisco Algaba Chueco
In this post we discuss a topic that everyone will have heard of. Let’s talk about migraines, a disorder that hides a huge ph
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10th Mar 2021
Polo-like kinase (Plk1) substrates and mitosis
Polo-like kinase (Plk1)
Polo-like kinase (Plk1), is a serine/threonine kinase that is active during mitosis (Hamanaka et al., 1995). Its name is derived from
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10th Mar 2021
PhD Interview tips
It’s not uncommon now for Masters or Undergraduate students to present some data or data that they produced during their research for a PhD interview process. Sometimes this can be in front
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10th Mar 2021
Barrett’s Oesophagus to Oesophageal Adenocarcinoma – Review
Oesophageal Adenocarcinoma is on the rise globally affecting more than 450,000 people worldwide (Pennathur, Gibson et al. 2013). Once diagnosed overall 5-year survival ranges from 15 % to 2
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10th Mar 2021
Metabolism or pluripotency – which regulates which? A chicken or the egg story.
By Sophie Arthur
How many diseases and conditions do you think exist in this world? Thousands? Hundreds of thousands? Maybe even millions? Unfortunately, I don’t know the answer. But what I
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10th Mar 2021
Investigating orthohantavirus infections with proteomics
Sarah Brun Bar-Yaacov PhD Candidate, University of Liverpool
Orthohantaviruses are a group of segmented negative-sense RNA viruses maintained as asympto
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10th Mar 2021
The Ubiquitin Proteasome System in Neurodegenerative disease
By Sinead Kinsella PhD
The Ubiquitin Proteasome System (UPS)
The Ubiquitin Proteasome System (UPS) is a regulatory machinery for protein turnover in t
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10th Mar 2021
An insight into the topology of the Enteric Nervous System
The Enteric Nervous system (ENS) is one of the largest subdivisions of the Peripheral Nervous System. This remarkable system is embedded between sheets of smooth muscle cells of the intestinal
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10th Mar 2021
HMGB1 in inflammation and cancer
HMGB1 Functional Overview
High mobility group box 1 (
HMGB1), a member of the high-mobility group (HMG) family, was first identified in the thymus in 1973 an
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9th Mar 2021
Immuno Oncology: If cancer was a pathogen, would a vaccine be able to destroy it?
Thanks to the great intuitions of brilliant scientists like Louis Pasteur, Edward Jenner, Robert Koch, Emil von Behring, Gaston Leon Ramon, Albert Sabin, Jonas Salk in the past century, the
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9th Mar 2021
miRNAs as therapeutics and biomarkers for pancreatic cancer
Pancreatic cancer survival rates
Despite
recent advances in our understanding of this disease, pancreatic cancer is one
of the world’s most lethal malignan
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9th Mar 2021
​The Complement System - pathways & function in the immune system
The Complement System Function
Gone are the days when the complement system was considered solely a companion of its impressive adaptive immune system counte
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9th Mar 2021
Estrogen and Breast Cancer: a Nuclear (Receptor) War
By Dr. Lisa Dwane, Postdoctoral Researcher, Royal College of Surgeons in Ireland
The first link between estrogen and breast cancer was made in the l
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9th Mar 2021