Therapeutic Antibody & Biosimilar ELISA Kits
Therapeutic antibody & biosimilar ELISA kits
Highly sensitive, quantitative free-drug and anti-drug-antibody (ADA) ELISA kits for pharmacokinetic, immunogenicity and biosimilarity studies — covering 30+ biologic drugs including adalimumab, trastuzumab, pembrolizumab, nivolumab, rituximab and tocilizumab.
Our TDM & ADA ELISA range
Multiple options and formats to support the full drug-monitoring workflow.
Therapeutic mAb ELISA
Screening & quantification of biologic drugs in serum and plasma.
Biosimilar ELISA
For QC, PK and biosimilarity assessment vs the reference product.
ADA ELISA
Detect anti-drug antibodies — qualitative, quantitative and free/total.
Custom ELISA
Bespoke assay development for your drug or target on request.
Built for PK & immunogenicity studies
Highly sensitive
Detection in the ng/mL range in serum and plasma.
Multiple formats
Qualitative, quantitative and free/total kits for full screening.
Low sample volume
Under 25 µl of sample per test.
Fast results
Complete in 70–140 minutes.
High recovery
85–115% recovery, validated in human samples.
One-year shelf life
Manufactured to ISO 13485 with lot-to-lot consistency.
Sandwich ELISA detection principle
Capture
Pre-coated capture reagent binds the drug or ADA from serum/plasma.
Detect
An enzyme-linked detection antibody binds the captured analyte.
Develop
Substrate produces a colour change proportional to analyte level.
Read
Measure OD on a plate reader and read off the standard curve.
Therapeutic drug-monitoring ELISA kits
70 free-drug and anti-drug-antibody kits across the major biologic drug classes. Filter by therapeutic area or format, or search by drug.
What these kits measure
Therapeutic mAb & biosimilar (free drug): quality control during development and manufacture, biosimilarity assessment against the reference product, pharmacokinetic (PK) studies to guide dosing, and monitoring of drug levels in patient samples during clinical development.
Anti-drug antibodies (ADA): immunogenicity assessment, response-variability analysis between patients, biosimilarity immunogenicity profiling, and free-vs-total ADA measurement using acid-dissociation to break drug–ADA complexes.
cGMP & ISO certified
Manufactured in state-of-the-art facilities to the highest standards for reproducible, reliable results.
Frequently asked questions
What can therapeutic-antibody ELISA kits be used for?
Free-drug kits quantify a biologic in serum or plasma for QC, biosimilarity and PK studies; ADA kits detect anti-drug antibodies for immunogenicity assessment. All kits are for research use only.
Do you offer free-drug and total (ADA) formats?
Yes — qualitative, quantitative and free/total ADA formats are available. Free/total ADA kits use acid dissociation to break drug–ADA complexes so both free and complexed ADA can be measured.
How sensitive are the kits and how much sample do they need?
Detection is in the ng/mL range with recovery of 85–115%, typically using under 25 µl of sample and completing in 70–140 minutes.
Can you develop a custom drug-monitoring ELISA?
Yes. If you don’t see your biologic listed, our team can develop a custom free-drug or ADA ELISA on request — get in touch via the contact page.
Don’t see your biologic?
We cover 30+ therapeutic antibodies and biosimilars, and our PhD-level team can develop a custom free-drug or ADA ELISA for your drug.
Request a custom ELISA