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Non-Human Primate Multiplex ELISA Panels

GeniePlex Multiplex · Non-Human Primate

Non-human primate multiplex immunoassay

Measure up to 28 NHP analytes simultaneously from as little as 15 µL of serum, plasma, or cell culture supernatant — validated cytokines, chemokines, growth factors, and neurotrophins for Rhesus and Cynomolgus macaque research.

Tested in Rhesus Macaque  ·  Cynomolgus Macaque
28
Validated Analytes
15 µL
Sample Volume
2 hr
Protocol Time
< 10%
Intra-assay CV
Section 01

Pre-mixed NHP multiplex panels

Three ready-to-order panels covering the most commonly requested NHP inflammatory and growth-factor analytes. All panels include 96 tests.

SKU Panel Analytes
MKAMPM001 NHP Th1/Th2 6-Plex IFNγ, IL-2, IL-4, IL-6, IL-10, TNFα
MKAMPM002 NHP Th1/Th2/Th17 7-Plex IFNγ, IL-2, IL-4, IL-6, IL-10, IL-17A, TNFα
MKAMPM003 NHP IGF-I & IGF-II 2-Plex IGF-I, IGF-II
Section 02

Cytokine release syndrome & COVID panels

Pre-configured panels for cytokine storm and SARS-CoV-2 research in macaques.

SKU Panel Analytes
MKAMCOV01NHP COVID-19 Multiplex CytokineIL-2, IL-10, IP-10/CXCL10, MCP-1/JE/CCL2, TNFα
MKAMCOV02NHP Cytokine Storm 3-PlexIL-6, IL-10, IFNγ
MKAMCOV04NHP Cytokine Storm 5-PlexIL-6, IL-10/CSIF, IFNγ, MCP-1/JE/CCL2
MKAMCOV03NHP Cytokine Storm 7-PlexIL-6, IL-10/CSIF, IFNγ, TNFα, IL-1β, IL-8/CXCL8, MCP-1/JE/CCL2
MKAMCOV05NHP 8-Plex Cytokine Release SyndromeIL-6, IL-10/CSIF, IFNγ, TNFα, IL-1β, IL-8/CXCL8, MCP-1/JE/CCL2
Section 03

Validated NHP analytes

All 28 individual analytes are available as single-plex kits or in custom multiplex configurations. Sensitivity ranges (LOD / LLOQ / ULOQ) are measured in pg/mL. Group 1 covers core inflammatory and Th1/Th2/Th17 cytokines; Group 2 covers growth factors, neurotrophins, and extended cytokines.

Group Analyte LOD (pg/mL) LLOQ (pg/mL) ULOQ (pg/mL)
G1IL-12p70< 3< 10> 2,000
G1Eotaxin/CCL11< 5< 10> 2,000
G1IFNγ< 5< 10> 5,000
G1IL-10/CSIF< 2< 5> 5,000
G1IL-17A/CTLA-8< 2< 5> 2,000
G1IL-1β< 5< 10> 5,000
G1IL-1RA< 5< 10> 2,000
G1IL-2< 5< 10> 5,000
G1IL-4< 1< 5> 2,000
G1IL-6< 2< 5> 5,000
G1IL-8/CXCL8< 1< 1> 1,000
G1IP-10/CXCL10< 3< 10> 2,000
G1MCP-1/JE/CCL2< 2< 5> 5,000
G1MCP-3/MARC/CCL7< 2< 5> 5,000
G1RANTES/CCL5< 5< 10> 5,000
G1TNFα< 1< 2> 5,000
G2β-NGF/NGFB< 10< 20> 5,000
G2FGF basic/FGF-2/HBGH-2< 20< 30> 10,000
G2IL-5< 5< 10> 5,000
G2MIG/CXCL9< 5< 10> 5,000
G2SDF-1< 10< 20> 5,000
G2TGFα/TGF-type I/ETGF< 10< 20> 5,000
G2VEGF-A< 10< 20> 5,000
G2BDNF< 5< 10> 5,000
G2IFN-α/IFNA< 10< 20> 5,000
G2GM-CSF/CSF-2< 5< 10> 5,000
G2IL-21< 5< 10> 5,000
G2CCL3/SCYA3/MIP-1α< 10< 20> 5,000

LOD — Limit of Detection  ·  LLOQ — Lower Limit of Quantification  ·  ULOQ — Upper Limit of Quantification. All values determined in standard diluent buffer.

Section 04

How GeniePlex works

GeniePlex bead-based multiplex technology uses multiple bead populations differentiated by size and fluorescence intensity. Combined with up to 12 fluorescence intensity levels per bead size, GeniePlex can measure up to 24 analytes simultaneously from a single 15 µL sample.

Bead populations are read on any flow cytometer equipped with either a single 488 nm laser or dual 488 nm and 633/640 nm lasers. Bead classification dye emits at 700 nm; PE reporter dye at 575 nm. See the flow cytometer setup guide for instrument-specific configuration.

Features & benefits

Multiplex
2–24 analytes from a single sample
Fast
2-hour protocol — same-day results
Sensitive
As low as < 1 pg/mL per analyte
Dynamic Range
LOD < 20 pg/mL  ·  ULOQ > 5,000 pg/mL
Precision
Intra-assay CV < 10%  ·  Inter-assay CV < 20%
Low Volume
Only 15 µL of sample required
Validated
Cross-reactivity tested in our lab
Sample Types
Serum, plasma, supernatant, lysates
Section 05

Data analysis & support

Comprehensive support for instrument setup, protocol troubleshooting, and citation searches.

Need a custom panel or volume pricing?

Our team will help you assemble a custom NHP multiplex panel from any combination of validated analytes — including additional analytes not listed above.

Request a quote Contact us