EMP1
EMP1 (epithelial membrane protein 1) is a membrane protein of the PMP-22/EMP/MP20 family. It is involved in the apoptotic process and bleb assembly, and is also known by the aliases TMP and CL-20. Browse Assay Genie's current range of EMP1 research reagents below, or read on for the biology behind the target.
EMP1, or epithelial membrane protein 1, is a membrane-associated protein that belongs to the PMP-22/EMP/MP20 family. Current gene annotation describes it as involved in the apoptotic process and in bleb assembly, and places it in the plasma membrane. These annotations make EMP1 a useful candidate for studies of how membrane proteins contribute to cell death and to changes in cell surface morphology.
The human EMP1 gene encodes a protein of 157 amino acids. Orthologues are present in the mouse and the rat, both named Emp1, which allows the protein to be studied in common experimental models. Because EMP1 is a member of a family that also includes EMP3, comparing family members can help researchers interpret expression and localisation findings.
The protein is also recorded under the aliases TMP and CL-20. When searching the literature or designing experiments around the EMP1 gene or EMP1 protein, it is worth including these alternative names. The source annotation for this entry is brief, so detailed mechanisms should be confirmed against primary literature.
EMP1 is annotated as involved in the apoptotic process, making it relevant to studies of programmed cell death.
EMP1 is located in the plasma membrane, so it is of interest for work on membrane protein organisation.
EMP1 is annotated as involved in bleb assembly, linking it to research on membrane morphology and dynamics.
As a member of the PMP-22/EMP/MP20 family, EMP1 can be compared with related proteins such as EMP3.
EMP1 is annotated as being involved in the apoptotic process and in bleb assembly, and it is located in the plasma membrane. It belongs to the PMP-22/EMP/MP20 family of membrane proteins. Beyond these annotations, its detailed molecular function is not described in the source data.
The approved HGNC name is epithelial membrane protein 1, with the symbol EMP1. Aliases include TMP and CL-20. Using all of these names is useful when searching databases and publications for work on this gene and its protein product.
Yes. Orthologues named Emp1 exist in both the mouse and the rat, so the gene can be studied in standard rodent models. Check the datasheet of any product for its validated reactivity.
A related epithelial membrane protein family member with products at Assay Genie.
Gene and protein annotations from HGNC, NCBI Gene and UniProt P54849; product specifications from Assay Genie datasheets.