ZNF232

ZNF232

Target · Zinc finger transcription factor

ZNF232 Zinc finger protein 232 · ZSCAN11

ZNF232 (zinc finger protein 232, also known as ZSCAN11) is a nuclear member of the krueppel C2H2-type zinc-finger protein family. It may be involved in transcriptional regulation, and it carries a SCAN domain. Browse Assay Genie's current range of ZNF232 research reagents below, or read on for the biology behind the target.

Nuclear proteinC2H2 zinc finger, SCAN domainPredicted transcription factor
444 aa
Protein length
~51 kDa
Molecular weight
17p13.2
Gene locus
C2H2 zinc finger
Protein family
Target information

What is ZNF232 (zinc finger protein 232)?

ZNF232 is annotated in UniProt as a protein that may be involved in transcriptional regulation. NCBI Gene summarises it as predicted to enable DNA-binding transcription factor activity, specifically RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding. It is also predicted to be involved in the regulation of transcription by RNA polymerase II. These assignments are predictions rather than experimentally established mechanisms, so the precise target genes of ZNF232 remain to be defined.

The ZNF232 protein belongs to the krueppel C2H2-type zinc-finger protein family. HGNC places the gene in two groups: zinc fingers C2H2-type, and SCAN domain containing. C2H2 zinc fingers are a common DNA-binding module in transcription factors, and the SCAN domain places ZNF232 among the ZSCAN proteins, which is reflected in its alias ZSCAN11. In terms of localisation, UniProt lists the protein in the nucleus, and NCBI Gene reports it in the nucleoplasm, consistent with a role in gene regulation.

The ZNF232 gene is the human gene with HGNC identifier HGNC:13026, NCBI Gene ID 7775 and UniProt accession Q9UNY5. Because its function is so far described mainly by prediction, ZNF232 is of interest to researchers who study uncharacterised members of the large zinc finger transcription factor family and who want to understand how SCAN domain proteins contribute to transcriptional control.

Transcription regulation studies

ZNF232 is predicted to act as a sequence-specific DNA-binding transcription factor in the regulation of transcription by RNA polymerase II.

Zinc finger protein biology

As a krueppel C2H2-type zinc-finger protein, ZNF232 offers a model for studying how this large family recognises DNA.

SCAN domain research

ZNF232 carries a SCAN domain and is classed with the SCAN domain containing group, relevant to studies of ZSCAN proteins.

Nuclear protein localisation

ZNF232 is located in the nucleus and nucleoplasm, making it a candidate for studies of nuclear factors involved in gene regulation.

Background

ZNF232 frequently asked questions

What does ZNF232 do?

UniProt states that ZNF232 may be involved in transcriptional regulation. NCBI Gene predicts it enables DNA-binding transcription factor activity and sequence-specific DNA binding at RNA polymerase II cis-regulatory regions. These functions are predicted, and the protein is found in the nucleus.

What other names does ZNF232 have?

The HGNC-approved name is zinc finger protein 232, and the gene symbol is ZNF232. The alias ZSCAN11 reflects the SCAN domain carried by the protein. HGNC lists no previous names for this gene. UniProt names the protein Zinc finger protein 232.

Which protein family does ZNF232 belong to?

ZNF232 belongs to the krueppel C2H2-type zinc-finger protein family. HGNC groups the gene under zinc fingers C2H2-type and SCAN domain containing. Mouse and rat orthologs are not given in the data supplied, so check the datasheet of any product for its validated reactivity.

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Related targets

Other zinc finger proteins and predicted transcription factors that are related to ZNF232 and have pages at Assay Genie.

Gene and protein annotations from HGNC, NCBI Gene and UniProt Q9UNY5; product specifications from Assay Genie datasheets.

ZNF232 Product listing

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