EEF1G
EEF1G (eukaryotic translation elongation factor 1 gamma, also known as EF1G) is a subunit of the elongation factor-1 complex, which delivers aminoacyl tRNAs to the ribosome. It is thought to help anchor that complex to other cellular components. Browse Assay Genie's current range of EEF1G research reagents below, or read on for the biology behind the target.
EEF1G encodes a subunit of the elongation factor-1 complex, the machinery responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome during translation elongation. UniProt annotates the protein as probably playing a role in anchoring the complex to other cellular components, which suggests a scaffolding contribution rather than a catalytic one.
The EEF1G protein, listed by UniProt as elongation factor 1-gamma, contains an N-terminal glutathione transferase domain. According to the NCBI Gene summary, this domain may be involved in regulating the assembly of multisubunit complexes that contain this elongation factor together with aminoacyl-tRNA synthetases. The EEF1G gene is found at 11q12.3, and orthologous genes named Eef1g are recorded in both mouse and rat, which makes rodent models a practical route for studying its function.
HGNC places EEF1G in the gene group of microRNA protein coding host genes, and EF1G is the alias in common use. Researchers studying translation often consider EEF1G alongside other elongation factors such as EEF1A1, EEF1A2 and EEF2, which act at different steps of the elongation cycle. Whether you are planning an EEF1G antibody experiment, an EEF1G ELISA kit assay or work with recombinant EEF1G protein, the key biological questions concern how this subunit organises the elongation factor-1 complex and its links to the aminoacyl-tRNA synthetases.
EEF1G is a subunit of the elongation factor-1 complex, which delivers aminoacyl tRNAs to the ribosome.
Its glutathione transferase domain may regulate assembly of multisubunit complexes containing elongation factor and aminoacyl-tRNA synthetases.
UniProt notes EEF1G probably anchors the elongation factor complex to other cellular components.
HGNC classifies EEF1G among microRNA protein coding host genes, linking it to regulatory RNA studies.
EEF1G is a subunit of the elongation factor-1 complex, which delivers aminoacyl tRNAs to the ribosome. UniProt states it probably plays a role in anchoring the complex to other cellular components, suggesting a structural or scaffolding function.
EEF1G is the HGNC symbol for eukaryotic translation elongation factor 1 gamma. EF1G is the recorded alias, and UniProt names the protein elongation factor 1-gamma. No previous HGNC names are listed for this gene.
Yes. Orthologous genes named Eef1g exist in both mouse and rat, so rodent models can be used to study it. For antibodies or other reagents, check the datasheet of any product for its validated reactivity.
Other eukaryotic elongation factors and regulators of translation elongation with products at Assay Genie.
Gene and protein annotations from HGNC, NCBI Gene and UniProt P26641; product specifications from Assay Genie datasheets.