FGFR1OP2
FGFR1OP2 (FGFR1 oncogene partner 2, also known as DKFZp564O1863) is a cytoplasmic protein of the SIKE family. It may be involved in the wound healing pathway, and it belongs to the STRIPAK complex gene group. Browse Assay Genie's current range of FGFR1OP2 research reagents below, or read on for the biology behind the target.
FGFR1OP2 is a protein whose function is not yet well defined. UniProt annotates it as a protein that may be involved in the wound healing pathway. This is consistent with the NCBI Gene summary, which describes the gene as predicted to be involved in response to wounding and predicted to act upstream of or within wound healing. These assignments are predictions rather than experimentally established roles, and they should be read as such when planning experiments with the FGFR1OP2 protein.
The NCBI Gene summary also predicts that FGFR1OP2 enables identical protein binding activity, which suggests it may interact with other copies of itself. UniProt lists its subcellular location as the cytoplasm, and the Alliance of Genome Resources predicts localisation to the cytosol. The protein is classed in the SIKE family, and HGNC places the FGFR1OP2 gene in the STRIPAK complex gene group. Orthologous genes, named Fgfr1op2, are present in both mouse and rat, which allows comparative work in common model organisms.
The name FGFR1 oncogene partner 2 is the approved HGNC full name, and DKFZp564O1863 is a listed alias. The name refers to FGFR1, but the source data do not describe any specific interaction with it, so the link should be treated as nomenclature only. Researchers interested in FGFR1OP2 may also look at related targets such as FGFR1 and FGFRL1 for context in fibroblast growth factor receptor biology.
FGFR1OP2 may be involved in the wound healing pathway, making it a candidate for studies of wound response.
Predicted identical protein binding activity makes FGFR1OP2 a subject for investigating homomeric interactions.
HGNC assigns FGFR1OP2 to the STRIPAK complex gene group, which frames work on related complex components.
FGFR1OP2 is located in the cytoplasm, supporting studies of its cytosolic distribution and function.
The function of FGFR1OP2 is not fully established. UniProt states that it may be involved in the wound healing pathway, and NCBI Gene reports predicted roles in response to wounding and wound healing, along with predicted identical protein binding activity.
FGFR1OP2 is the HGNC symbol for FGFR1 oncogene partner 2. The alias DKFZp564O1863 is also listed. UniProt classes the protein in the SIKE family, and HGNC places the gene in the STRIPAK complex gene group.
Yes. Orthologous genes named Fgfr1op2 are recorded for both mouse and rat, so the target can be studied in common rodent models. Check the datasheet of any product for its validated reactivity.
Fibroblast growth factor receptor family members that provide context for FGFR1OP2 research.
Gene and protein annotations from HGNC, NCBI Gene and UniProt Q9NVK5; product specifications from Assay Genie datasheets.