APMAP
APMAP (adipocyte plasma membrane associated protein) is a membrane protein with strong arylesterase activity that may play a role in adipocyte differentiation. It is also known as BSCv and, under its previous symbol, C20orf3. Browse Assay Genie's current range of APMAP research reagents below, or read on for the biology behind the target.
APMAP is an enzyme-like membrane protein that exhibits strong arylesterase activity. In biochemical assays it acts on the substrates beta-naphthyl acetate and phenyl acetate, which defines its catalytic profile as an arylesterase. UniProt also notes that it may play a role in adipocyte differentiation, although this function is described as possible rather than established.
The human APMAP gene encodes adipocyte plasma membrane-associated protein, which UniProt lists as belonging to the strictosidine synthase family. According to the NCBI Gene summary, the protein enables arylesterase activity and is located at the cell surface and in the membrane. Researchers studying the APMAP protein therefore typically consider it in the context of membrane biology and esterase activity. Mouse and rat orthologs, both named Apmap, are recognised, which allows the gene to be studied in rodent models.
The gene was formerly designated C20orf3, short for chromosome 20 open reading frame 3, and the alias BSCv also appears in the literature and databases. The HGNC name, adipocyte plasma membrane associated protein, reflects the original association with adipocyte plasma membranes. When searching for reagents or literature on this target, it helps to include these alternative names alongside APMAP.
APMAP shows strong arylesterase activity towards beta-naphthyl acetate and phenyl acetate, making it a subject for studies of esterase function.
UniProt annotates APMAP as potentially involved in adipocyte differentiation, so it is of interest in adipocyte biology.
APMAP is located at the cell surface and in the membrane, supporting work on membrane-associated enzymes.
As a member of the strictosidine synthase family, APMAP is a candidate for comparative studies of family function and evolution.
APMAP exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate as substrates. UniProt also states that it may play a role in adipocyte differentiation. NCBI Gene describes it as enabling arylesterase activity and being located at the cell surface and in the membrane.
APMAP stands for adipocyte plasma membrane associated protein. The gene is also known as BSCv, and its previous symbol was C20orf3, derived from the earlier name chromosome 20 open reading frame 3. UniProt uses the name adipocyte plasma membrane-associated protein.
Yes. Mouse and rat orthologs, each named Apmap, are listed for the human gene, so the protein can be studied in common rodent models. Please check the datasheet of any product for its validated reactivity.
Other membrane enzymes, esterases and adipocyte biology markers with products at Assay Genie.
Gene and protein annotations from HGNC, NCBI Gene and UniProt Q9HDC9; product specifications from Assay Genie datasheets.