BCAS4
BCAS4 (breast carcinoma amplified sequence 4) is a human protein of the cappuccino family, also known as FLJ20495 and CNOL. It is predicted to localise to the cytoplasm and to form part of the BLOC-1 complex. Browse Assay Genie's current range of BCAS4 research reagents below, or read on for the biology behind the target.
BCAS4 is a protein assigned to the cappuccino family. No curated functional annotation is currently available for it in UniProt, so its precise biochemical role remains to be defined. Genome-level predictions from the Alliance of Genome Resources indicate that BCAS4 is located in the cytoplasm and is part of the BLOC-1 complex, a multi-subunit assembly. These are predictions rather than experimentally established findings, and they are the main guide to where BCAS4 may act in the cell.
The BCAS4 gene lies at chromosome 20q13.13 and encodes a protein that UniProt lists as Breast carcinoma-amplified sequence 4 (accession Q8TDM0). The gene is catalogued by HGNC as HGNC:14367 and by NCBI Gene as 55653. Researchers studying the gene or protein will find it listed under the symbol BCAS4 and under the aliases FLJ20495 and CNOL. Orthologues in mouse and rat are not specified in the data used for this page, so cross-species work should be checked against current database records.
The official name, breast carcinoma amplified sequence 4, reflects the context in which the gene was first designated. The available sources do not describe a disease mechanism, expression pattern or interaction partner for BCAS4, and none is asserted here. Its membership of the cappuccino family and its predicted association with BLOC-1 make it a candidate for studies of BLOC-1-related cytoplasmic biology. Reagents for BCAS4 detection, such as an anti-BCAS4 antibody or a BCAS4 ELISA kit, can support that characterisation.
BCAS4 is predicted to be part of the BLOC-1 complex, so it is of interest when examining how that assembly is composed.
As a member of the cappuccino family, BCAS4 provides a point of comparison with related family proteins.
BCAS4 is predicted to be cytoplasmic, making it a subject for subcellular localisation and expression studies.
The gene name refers to a breast carcinoma amplified sequence, which makes BCAS4 relevant to researchers exploring genes designated in that context.
The function of BCAS4 has not been curated in UniProt. Genome-level predictions place it in the cytoplasm and as part of the BLOC-1 complex, but these are predicted rather than experimentally confirmed. Its precise molecular role therefore remains to be established.
BCAS4 stands for breast carcinoma amplified sequence 4. UniProt lists the protein as Breast carcinoma-amplified sequence 4, and the aliases FLJ20495 and CNOL also appear in HGNC records. HGNC has no previous names recorded for this gene.
BCAS4 is assigned to the cappuccino family, but the data supplied do not specify mouse or rat orthologues. Check current ortholog records before planning cross-species work, and check the datasheet of any product for its validated reactivity.
Other BLOC-1 complex subunits and cappuccino family proteins that may be of interest alongside BCAS4.
Gene and protein annotations from HGNC, NCBI Gene and UniProt Q8TDM0; product specifications from Assay Genie datasheets.