OSCP1
OSCP1, the organic solute carrier partner 1 (also known as NOR1 or C1orf102), is a human protein that may be involved in drug clearance in the placenta. It is associated with transmembrane transport and xenobiotic detoxification. Browse Assay Genie's current range of OSCP1 research reagents below, or read on for the biology behind the target.
OSCP1 is annotated in UniProt as a protein that may be involved in drug clearance in the placenta. The NCBI Gene summary adds that it enables transmembrane transporter activity and is involved in xenobiotic detoxification by transmembrane export across the plasma membrane. Together, these annotations place OSCP1 among the proteins that help remove foreign compounds from cells.
In terms of localisation, UniProt lists the basal cell membrane, and NCBI Gene describes the protein as located in the basal plasma membrane and cytoplasm. This pattern is consistent with a role at the cell surface in export processes, although the detailed mechanism is not defined in the sources used here. Researchers studying the OSCP1 protein therefore commonly consider membrane and cytoplasmic compartments when designing experiments.
The human OSCP1 gene is the subject of HGNC entry HGNC:29971 and is recorded under the full name organic solute carrier partner 1. It has also been known as NOR1, and its previous symbol and name were C1orf102 and chromosome 1 open reading frame 102. HGNC places it in the gene group small nucleolar RNA protein coding host genes. Mouse and rat each have an orthologous gene, named Oscp1, which allows comparative work in common model organisms.
OSCP1 may be involved in drug clearance in the placenta, making it a candidate for studying how compounds are handled at this tissue.
OSCP1 is involved in xenobiotic detoxification by transmembrane export across the plasma membrane, relevant to studies of cellular defence against foreign compounds.
OSCP1 enables transmembrane transporter activity, so it is of interest in research on how solutes and compounds cross cell membranes.
OSCP1 is found at the basal plasma membrane and in the cytoplasm, supporting work on polarised membrane distribution.
UniProt states that OSCP1 may be involved in drug clearance in the placenta. NCBI Gene adds that it enables transmembrane transporter activity and contributes to xenobiotic detoxification by export across the plasma membrane. Its precise molecular mechanism is not fully described in these sources.
OSCP1 stands for organic solute carrier partner 1, and the protein is listed in UniProt as Protein OSCP1. It is also known as NOR1, and earlier records use the symbol C1orf102, from the name chromosome 1 open reading frame 102.
Yes. Both mouse and rat have an ortholog named Oscp1, so rodent models can be used to study the gene. Check the datasheet of any product for its validated reactivity before choosing a reagent for a particular species.
Other membrane transporters and xenobiotic-handling proteins with products at Assay Genie.
Gene and protein annotations from HGNC, NCBI Gene and UniProt Q8WVF1; product specifications from Assay Genie datasheets.