FAM171B
FAM171B (family with sequence similarity 171 member B) is a human protein of the FAM171 family, also known as KIAA1946 and FLJ34104. It is predicted to be a membrane protein with a possible role at the synapse, and its biological function remains uncharacterised. Browse Assay Genie's current range of FAM171B research reagents below, or read on for the biology behind the target.
FAM171B is a member of the FAM171 family. No curated functional annotation is currently available for the protein, so its molecular mechanism has not been defined. Genome-resource predictions place FAM171B in the membrane and suggest it is active in the synapse, and UniProt lists cytoplasmic granule and membrane as subcellular locations. These annotations are a starting point for experimental work rather than a established mechanism.
The human FAM171B gene encodes the protein catalogued in UniProt as Q6P995 and in NCBI Gene as 165215. Researchers studying the FAM171B protein will find that its predicted membrane and synaptic association is the main guide to likely cellular context. Tissue expression data are not part of the source annotation used here, so expression patterns should be confirmed in the system under study. The mouse ortholog is designated Fam171b, which allows comparative work in mouse models.
The symbol FAM171B follows the HGNC naming scheme for families of sequence-similar genes whose functions were not known at the time of naming. The gene was previously named KIAA1946 and is also referred to as FLJ34104, and older literature or databases may use these names. HGNC does not currently assign FAM171B to a wider gene group, and no disease association is given in the sources used for this page.
FAM171B is predicted to be a membrane protein, making it a candidate for studies of membrane-associated proteins of unknown function.
Genome resource predictions suggest FAM171B is active in the synapse, which frames investigation of its role in synaptic compartments.
UniProt lists cytoplasmic granule as a subcellular location, pointing to questions about how FAM171B is distributed within cells.
As a FAM171 family member, FAM171B can be examined alongside related proteins to explore shared and distinct features.
The function of FAM171B has not been defined in the sources used here. It belongs to the FAM171 family and is predicted to be located in the membrane and active in the synapse. UniProt also lists cytoplasmic granule and membrane as subcellular locations.
FAM171B stands for family with sequence similarity 171 member B. It is also known as KIAA1946 and FLJ34104. HGNC records KIAA1946 as a previous symbol and as a previous name, so older publications and databases may use it.
A mouse ortholog, Fam171b, is recorded for the human gene, which supports comparative studies in mouse. No rat ortholog is given in the data used here. Check the datasheet of any product for its validated reactivity.
Other proteins named under the family with sequence similarity (FAM) scheme, which share a naming convention with FAM171B.
Gene and protein annotations from HGNC, NCBI Gene and UniProt Q6P995; product specifications from Assay Genie datasheets.