ANXA10
ANXA10 (annexin A10, also known as ANX14) is a member of the annexin family of calcium-dependent phospholipid-binding proteins. Family members are linked to the regulation of cellular growth and to signal transduction pathways, although the specific function of ANXA10 has not yet been determined. Browse Assay Genie's current range of ANXA10 research reagents below, or read on for the biology behind the target.
ANXA10 encodes annexin A10, a member of the annexin family. According to the NCBI Gene summary, members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The precise function of the ANXA10 gene has not yet been determined, and no functional annotation is currently provided in UniProt for the protein. Researchers working with ANXA10 should therefore treat its role as an open question and interpret findings with reference to the wider annexin family.
The protein is catalogued in UniProt under accession Q9UJ72 and is classed by UniProt as belonging to the annexin family. HGNC places the gene in the Annexins group under the approved name annexin A10. No subcellular location has been annotated for the protein in UniProt, and tissue expression is not described in the sources used for this page. A mouse ortholog, Anxa10, is recorded for the gene.
The gene was previously known by the alias ANX14, a name that reflects the numbering used for annexins before the A-series nomenclature was applied consistently. Because the family shares calcium-dependent phospholipid binding, comparison with other annexins such as ANXA1, ANXA2 or ANXA5 is a common starting point when designing experiments on ANXA10 biology. Studies of the ANXA10 protein often rely on this family context, since direct functional data remain limited.
ANXA10 belongs to a calcium-dependent phospholipid-binding family, making it a point of comparison when studying how annexin members differ from one another.
Annexin family members are described as playing a role in the regulation of cellular growth, a context in which ANXA10 can be investigated.
Annexins are implicated in signal transduction pathways, so ANXA10 is relevant to work exploring how family members contribute to cellular signalling.
The function of ANXA10 has not yet been determined, so the protein is of interest for studies aiming to define its biological role.
ANXA10 is an annexin family member. According to NCBI Gene, annexins are calcium-dependent phospholipid-binding proteins that play a role in regulating cellular growth and in signal transduction pathways. The specific function of ANXA10 itself has not yet been determined, and UniProt provides no functional annotation.
The approved HGNC name is annexin A10 and the symbol is ANXA10. The alias ANX14 is also used in the literature. HGNC lists no previous names for the gene, and it sits in the Annexins gene group alongside the other ANXA genes.
A mouse ortholog, Anxa10, is recorded for the human gene. No rat ortholog is given in the data used here. Reactivity depends on the individual reagent, so check the datasheet of any product for its validated reactivity.
Other annexin family members involved in calcium-dependent phospholipid binding, cell growth regulation and signal transduction.
Gene and protein annotations from HGNC, NCBI Gene and UniProt Q9UJ72; product specifications from Assay Genie datasheets.