FAM151A
FAM151A (family with sequence similarity 151 member A) is a membrane-associated protein of the menorin family, also known as C1orf179 and MGC27169. Its biochemical function has not been defined in the sources available, but it has been located to extracellular exosomes. Browse Assay Genie's current range of FAM151A research reagents below, or read on for the biology behind the target.
FAM151A is a protein assigned to the menorin family. No curated functional annotation is currently recorded for it in UniProt, so its molecular mechanism, substrates and binding partners remain to be established. UniProt lists it as a membrane protein, and NCBI Gene, drawing on the Alliance of Genome Resources, reports that it is located in extracellular exosomes. Researchers working with FAM151A protein should therefore treat it as a poorly characterised target and rely on the experimental context of each study.
The FAM151A gene is the human gene designated family with sequence similarity 151 member A, with the HGNC identifier HGNC:25032. The "family with sequence similarity" nomenclature is a general naming scheme applied to genes grouped by sequence relatedness rather than by established function. The gene was previously named chromosome 1 open reading frame 179 (C1orf179), and MGC27169 is also recorded as an alias. Orthologous genes named Fam151a are present in mouse and rat, which allows comparative work in rodent models.
In terms of disease relevance, the NCBI Gene summary states that FAM151A is implicated in colorectal adenocarcinoma. The summary does not describe the nature of this association, so it is best read as a pointer for further investigation, for example in studies of exosome cargo or tumour-associated membrane proteins, rather than as evidence of a defined pathway.
FAM151A is implicated in colorectal adenocarcinoma, making it a candidate for studies of its role in this tumour type.
FAM151A is located in extracellular exosomes, so it is relevant to studies of exosome composition and vesicle-associated proteins.
As a membrane protein with no defined function, FAM151A is a subject for work on localisation, topology and cellular role.
FAM151A belongs to the menorin family, supporting comparative studies of how related proteins are conserved and diverge.
The molecular function of FAM151A has not been annotated in UniProt. It is a membrane protein of the menorin family and is located in extracellular exosomes. NCBI Gene reports that it is implicated in colorectal adenocarcinoma, but the mechanism is not described.
FAM151A stands for family with sequence similarity 151 member A. It was previously named chromosome 1 open reading frame 179, with the symbol C1orf179, and MGC27169 is a recorded alias. UniProt names the protein Protein FAM151A.
Yes. Orthologues named Fam151a are recorded in both mouse and rat, so rodent models can be used for comparative study of this gene. Check the datasheet of any product for its validated reactivity.
Other proteins from the family with sequence similarity (FAM) gene nomenclature with products at Assay Genie.
Gene and protein annotations from HGNC, NCBI Gene and UniProt Q8WW52; product specifications from Assay Genie datasheets.