ENHO
ENHO (energy homeostasis associated) encodes adropin, a secreted protein involved in the regulation of glucose homeostasis and lipid metabolism. The gene was previously designated C9orf165 and is also known by the alias UNQ470. Browse Assay Genie's current range of ENHO research reagents below, or read on for the biology behind the target.
The ENHO gene encodes adropin, a secreted protein that is involved in the regulation of glucose homeostasis and lipid metabolism. NCBI Gene annotation describes it as enabling hormone activity and as being involved in energy homeostasis, and places its activity in the extracellular space. These annotations make adropin a useful subject for researchers studying how metabolic state is communicated between tissues.
The ENHO gene is located at 9p13.3 and produces a small secreted polypeptide. UniProt records its subcellular location as secreted, consistent with a role as a circulating or extracellular signalling factor. Researchers working with the adropin protein, whether through an ENHO antibody, an ENHO ELISA kit or other reagents, are generally interested in its abundance and regulation in the context of energy balance. A mouse ortholog, Enho, is recognised, which supports comparative work in rodent models of metabolism.
The gene symbol ENHO stands for energy homeostasis associated, a name that reflects the functional annotation of the locus. Before this symbol was adopted, the gene was known as chromosome 9 open reading frame 165 (C9orf165). The alias UNQ470 is also found in the literature and in databases. Because the source annotation is concise, the precise receptors and downstream pathways are not covered here, and readers should consult primary literature for mechanistic detail.
Adropin is involved in the regulation of glucose homeostasis, making ENHO relevant to studies of how glucose levels are controlled.
ENHO is annotated as involved in lipid metabolism, supporting investigation of how this secreted protein relates to lipid handling.
The ENHO gene is associated with energy homeostasis, a central theme in metabolic and endocrine research.
Annotated with hormone activity and extracellular activity, adropin is a candidate for studying secreted factors in inter-tissue communication.
ENHO encodes adropin, a secreted protein involved in the regulation of glucose homeostasis and lipid metabolism. NCBI Gene annotation adds that it enables hormone activity and is involved in energy homeostasis, with activity in the extracellular space.
ENHO stands for energy homeostasis associated, and the encoded protein is called adropin. The gene was previously named chromosome 9 open reading frame 165, with the symbol C9orf165, and it also carries the alias UNQ470.
A mouse ortholog, Enho, is recognised, which allows the gene to be studied in mouse models of metabolism. Check the datasheet of any product for its validated reactivity before choosing a reagent for a particular species.
Other secreted hormones and metabolic regulators studied alongside energy homeostasis, glucose control and lipid metabolism.
Gene and protein annotations from HGNC, NCBI Gene and UniProt Q6UWT2; product specifications from Assay Genie datasheets.