CD200R1L
CD200R1L (CD200 receptor 1 like, also known as CD200RLa or CD200R2) is a membrane glycoprotein of the CD200R family. It is annotated as a possible receptor for the CD200/OX2 cell surface glycoprotein. Browse Assay Genie's current range of CD200R1L research reagents below, or read on for the biology behind the target.
CD200R1L is annotated in UniProt as a protein that may act as a receptor for the CD200/OX2 cell surface glycoprotein. Its function has not been firmly established, and the NCBI Gene summary describes it as predicted to enable signalling receptor activity. It is predicted to be active on the external side of the plasma membrane and to be located at the cell surface and in the membrane, consistent with a receptor role.
The protein is encoded by the CD200R1L gene and belongs to the CD200R family. HGNC places it in the C2-set domain containing gene group. UniProt lists it as a membrane protein under the name cell surface glycoprotein CD200 receptor 2. Researchers studying this target should note that the CD200R1L gene and protein are described largely through prediction, so experimental context matters when interpreting results.
The gene has been known by several names, including CD200 receptor 1-like, CD200RLa and CD200R2. The NCBI Gene summary also predicts involvement in the regulation of the neuroinflammatory response, although this is an inferred annotation rather than an established function. A mouse ortholog, Cd200r1l, is recorded, which may be relevant for comparative work on the CD200 receptor family.
CD200R1L is annotated as a possible receptor for CD200/OX2, making it of interest when studying how CD200R family members interact with this ligand.
The gene is predicted to be involved in regulating the neuroinflammatory response, which makes it a candidate for studies of inflammatory control.
Predicted to be active on the external side of the plasma membrane, it is relevant to work on membrane-bound signalling receptors.
As a CD200R family member with a mouse ortholog, Cd200r1l, it supports comparative studies across related receptors and species.
UniProt states that CD200R1L may be a receptor for the CD200/OX2 cell surface glycoprotein. The NCBI Gene summary predicts signalling receptor activity and a role in regulating the neuroinflammatory response. These are predicted functions, and the protein remains incompletely characterised.
CD200R1L stands for CD200 receptor 1 like. Aliases include CD200RLa and CD200R2, and the previous name was CD200 receptor 1-like. UniProt lists the protein as cell surface glycoprotein CD200 receptor 2, so all of these names may appear in the literature.
A mouse ortholog, Cd200r1l, is recorded for the human gene. No rat ortholog is given in the data supplied. The protein belongs to the CD200R family. Check the datasheet of any product for its validated reactivity.
Other CD antigens, cell surface receptors and immune-related membrane proteins with products at Assay Genie.
Gene and protein annotations from HGNC, NCBI Gene and UniProt Q6Q8B3; product specifications from Assay Genie datasheets.