PRB1
PRB1 (proline rich protein BstNI subfamily 1) is a human gene encoding basic salivary proline-rich protein 1, a secreted member of the proline rich protein group. It is also known by the aliases PM, PMF, PMS, PRB1M and PRB1L. Browse Assay Genie's current range of PRB1 research reagents below, or read on for the biology behind the target.
PRB1 is the HGNC-approved symbol for the gene that encodes basic salivary proline-rich protein 1, the protein name used by UniProt. The curated sources available for this target do not include a detailed functional annotation, so the biochemical mechanism of the PRB1 protein is not described here. What can be stated is its classification and location: UniProt lists the protein as secreted, and the NCBI Gene summary, provided by the Alliance of Genome Resources, reports that it is predicted to be located in the extracellular region.
The PRB1 gene is placed by HGNC in the gene group of proline rich proteins, and the protein name identifies it as a basic, salivary, proline-rich protein. Related genes in this group that are covered by Assay Genie target pages include PRB2 and PRB4, which share the proline rich protein BstNI subfamily naming. Researchers who study secreted proline-rich proteins can therefore consider PRB1 alongside these neighbouring family members.
PRB1 has been recorded under several aliases, including PM, PMF, PMS, PRB1M and PRB1L, which are worth searching when reviewing older literature or database entries. Its previous HGNC name, proline rich protein BstNI subfamily 1 (gene/pseudogene), shows that the nomenclature for this locus has been revised over time. The stable identifiers HGNC:9337, NCBI Gene 5542 and UniProt P04280 allow the target to be matched reliably across resources, whichever alias an earlier paper used.
PRB1 is named as a basic salivary proline-rich protein, making it a relevant target for studies of secreted proteins in this context.
UniProt lists PRB1 as secreted and NCBI Gene predicts an extracellular location, so it is of interest in extracellular protein studies.
HGNC groups PRB1 with the proline rich proteins, supporting comparative work alongside related members such as PRB2 and PRB4.
Multiple aliases and a revised gene/pseudogene name make PRB1 a useful case for reconciling identifiers across databases and literature.
The sources available for this page give no detailed functional annotation for PRB1. UniProt names it basic salivary proline-rich protein 1 and lists it as secreted, and NCBI Gene predicts an extracellular location. Specific molecular activities should be confirmed from primary literature.
PRB1 stands for proline rich protein BstNI subfamily 1. Aliases and previous symbols include PM, PMF, PMS, PRB1M and PRB1L, and UniProt uses the name basic salivary proline-rich protein 1. The previous HGNC name carried the qualifier gene/pseudogene.
HGNC places PRB1 in the proline rich proteins gene group. Related loci with similar naming include PRB2 and PRB4. No mouse or rat ortholog is specified in the data for this target, so check the datasheet of any product for its validated reactivity.
Other proline rich protein family members and related salivary secreted targets with products at Assay Genie.
Gene and protein annotations from HGNC, NCBI Gene and UniProt P04280; product specifications from Assay Genie datasheets.