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In Vivo Antibodies

In Vivo Functional Grade Antibodies

Low & Ultra-Low Endotoxin Antibodies

Assay Genie In Vivo Functional Grade Antibodies are ideal for scientists who need ultra-pure, low-endotoxin antibodies for demanding applications, including in vivo mouse studies, in vitro functional assays, and 3D Organoid platforms.


Using a proprietary multi‑step purification process, these antibodies are free from preservatives, stabilisers, and carrier proteins and have up to >98% purity. The range includes low‑endotoxin (<1.0 EU/mg), ultra‑low endotoxin (<0.5 EU/mg), and matched isotype control antibodies as well as biosimilar & bispecific antibodies for immune modulation and therapeutic development.

radio_button_checked    Low Endotoxin 
High purity and low endotoxin levels (≤  1.0 EU/mg) antibodies for in vivo functional studies.
gps_not_fixed    Ultra Low Endotoxin 
With ≤0.5 EU/mg endotoxin levels, and Pathogen-free (IDEXX Impact tested).
toll   Bispecifics 
Antibodies designed for dual-target engagement and immune modulation.
donut_large   Biosimilars 
In vivo grade antibodies engineered to replicate reference biologics.

Industry Leading Quality

High Purity In Vivo mAbs

check_circle   Low & Ultra Low Endotoxin Formats
≤ 0.5 - ≤ 1.0 EU/mg and no detectable leachable protein A or aggregates.
check_circle   High Purity
Multi-step purification and extensive QC to ensure high reproducibility between lots.
check_circle   Formulation
No preservatives, stabilisers or carrier protein. Sterile PBS free from K+ or Ca2+.
check_circle   Comprehensive
200+ functional-grade antibodies  & isotype controls for all research areas.
chevron_right   In vivo Functional Studies
Functional Studies with mAbs on tumor growth & cancer progression. Depleting T-cells/B-cells to manipulate immune system.
chevron_right   In Vitro Assays
In vitro functional assays, such as blocking, neutralization, or activation. Also suitable for in vitro 3D organoid and organ-on-chip applications.
chevron_right   Tested Applications
Costimulation, Cell Depletion, Neutralization, Blocking, ELISA, FC, ICC, IHC-PE, IHC-FF, IP, WB, CODEX®, CyTOF®
Example QC & Bionalysis of PD-1 [RMP1-14] mAb 
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A: Endotoxin Analysis
Endotoxin ≤ 0.5 EU/mg for all 8 lots.
C: Non-reducing SDS Page
Non-reducing SDS-PAGE analysis demonstrating consistently high purity for all lots.
B: Chromataography Analysis
Size exclusion chromatography visualized by superimposing chromatograms for nine lots.
D: Reducing SDS Page
Reducing SDS-PAGE analysis demonstrates consistently high purity for all lots.
Efficacy & Tolerability Benchmarking
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Anti-PD-1 [RMP1-14 & 29F.1A12]
Anti-CTLA-4 [9H10]
Independent comparison of the in vivo efficacy and tolerability of clones of mAbs anti-PD-1 [RMP1-14 and 29F.1A12], anti-PD-L1 [10F.9G2], and anti-CTLA-4 [9H10] and isotype controls versus Vendor B using a CT26 syngeneic model (murine colorectal carcinoma derived from BALB/c mice). All antibodies had matching isotype controls, and phosphate-buffered saline (PBS) was used as a control.

Recent Citations

Featured in High-Impact Scientific Journals

Trusted by Scientists Worldwide

Making scientists smile

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"Even though Assay Genie is new to the market, we've been pleasantly surprised by the quality and performance of their antibodies. Their products have shown reliable results in our initial tests, and their team has been responsive and proactive in addressing our questions. It’s great to see a new company with such dedication to both product performance and customer service. We're excited to see where they go from here and look forward to continuing our partnership."


- Mathieu Desbuisson, Technician researcher, Ludwig Institute for Cancer Research, CHUV

In Vivo Antibodies for All Research Areas

Designed to support your research

Product
Reactivity
Clone
Application
Mouse
37.51
B, Costim, CyTOF®, FC, IHC FF, IP, WB
Mouse

1D3

B, CODEX®, Depletion, FC, IHC FF, IP, WB
Mouse

1A8

CODEX®, CyTOF®, D, FC, IHC FF, WB
Mouse

RMT3-23

B, CODEX®, FC, IF Staining, IHC, IHC FF
Product
Reactivity
Clone
Application

Mouse

ICRF44
CODEX®, FC, IF Staining, IHC FF

Mouse/Human

IM7
CODEX®, CyTOF®, ELISA Det, FC, ICC, IHC FF, IHC FFPE, IP, WB

Mouse/Human

IM7
CODEX®, CyTOF®, ELISA Det, FC, ICC, IHC FF, IHC FFPE, IP, WB

Human

DREG56
B, CODEX®, FC, IF, IHC FF, WB

Bovine, Hamster, Human, Mouse, Rat

1D11.16.8
IHC, N, WB
Product
Reactivity
Clone
Application

Mouse

145-2C11
Act, B, CODEX®, CyTOF®, Depletion, FA, FC, ICC, IF, IHC FF, WB

Mouse

145-2C11
Act, B, CODEX®, CyTOF®, Depletion, FA, FC, ICC, IF, IHC FF, WB

Mouse

30-H12

CODEX®, Costim, CyTOF®, Depletion, FC, IHC FF, WB

Mouse

30-H12
Costim, CyTOF®, Depletion, FC, IHC FF, WB

Mouse

GK1.5

B, Costim, CyTOF®, Depletion, FA, FC, IHC, IP

Mouse

53-6.7

B, CODEX®, CyTOF®, Depletion, FC, IHC FF, IP, WB

Mouse

53-6.7

B, CODEX®, CyTOF®, Depletion, FC, IHC FF, IP, WB

Mouse

2.43

Depletion, FA, FC, ICC, IF Staining, IHC FFPE, IP

Mouse

2.43

Depletion, FA, FC, ICC, IF Staining, IHC FFPE, IP

Mouse

PC61

B, CODEX®, Depletion, FA, FC, IHC FF, IP, WB

Mouse

PC61

B, CODEX®, Depletion, FA, FC, IHC FF, IP, WB

Mouse

RA3-6B2

Act, CODEX®, CyTOF®, Depletion, FA, FC, IHC FF, IP

Mouse

RA3-6B2

Act, CODEX®, CyTOF®, Depletion, FA, FC, IHC FF, IP

Mouse

1D3

B, CODEX®, Depletion, FC, IHC FF, IP, WB

Mouse

RB6-8C5

CyTOF®, Depletion, FC, IHC FF, IHC FFPE, IP, WB

Mouse

PK136

B, CyTOF®, Depletion, FC, IP, WB

Mouse

1A8

CODEX®, CyTOF®, Depletion, FC, IHC FF, WB

Mouse

1A8

CODEX®, CyTOF®, Depletion, FC, IHC FF, WB

Mouse

RB6-8C5

CyTOF®, Depletion, FC, IHC FF, IHC FFPE, IP, WB
Product
Reactivity
Clone
Application
Mouse
11B11
CyTOF®, ELISA Cap, ELISPOT, FA, ICC, IHC, IP, N

Popular In Vivo mAbs

Optimized to achieved the best results

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Fast Delivery

7 - 10  Business Day Lead Time after Manufacture
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Highly Cited

We develop high quality custom multiplex assays using the best technology
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PhD Level Support

Our team are trained to a PhD level to support your multiplex assay problems

Frequently asked questions

Customers may place an order in 3 ways. Orders can be made online via pro-forma invoice, on our website, or via email by emailing orders@assaygenie.com. If you wish to send a purchase order, you can find our company under "Assay Genie" or "Reagent Genie Ireland Ltd" on your ordering system. Alternatively, orders may be placed via your local distributor.
Our company can be found under the supplier name "Assay Genie" or "Reagent Genie Ireland Ltd." Still can't find us? Check if we are on your vendor system here. If not, we would be happy to fill out a new supplier form to be registered as a vendor. Alternatively, orders can be placed through your local distributor.
To find out if you can directly order from us or if your order must be made via a distributor click here. Information on your local distributor can be found on this page.
Inquiries can be made online via our 'Contact Us' page. You may also contact us via email at: info@assaygenie.com or orders@assaygenie.com, or by telephone on: +353 15639720. Alternatively, an inquiry can be made via your local distributor.
To create an Assay Genie account, click on 'Register' in the top right corner of the home page. On the registration page fill out the registration details. Once complete, click the 'Create Account' button. To login, click on 'Sign in' in the top right corner of the results page (beside 'Register'). Fill in your email and password and click the 'Sign in' button.
To change the currency of product prices click 'select currency' from the row of options at the top of screen of each web page. Options include: Euro (€), Pound (£), and US Dollar ($).
Once we have received your order a confirmation email will be sent to you. Details such as order number and estimated date of delivery will also be disclosed in this email.

Meet Some of the Genie Team!

At Assay Genie, we're here to help every step of the way. Whether you need guidance choosing the right product, updates on your order, or expert support after your purchase, we've got you covered.

  • Colm PhD, CEO
    Sean PhD, CSO
    Shane MSc, Sales Manager
    Beatriz, Logistics
  • David PhD, Partner Manager
    Marina PhD, Tech Support
    Joe MSc, Sales
    Miren PhD, Product Manager
  • Zac MSc, Operations Manager
    Natalia PhD, Tech Support
    José MSc, Development Manager

Additional Resources