Immuno-Oncology Discovery In Vivo Pack with Matched Isotype Controls A five-antibody discovery panel spanning the PD-1, PD-L1, CTLA-4 and LAG-3 checkpoints plus CD8alpha, with matched isotype controls. Each vial is a low-endotoxin (< 1.0 EU/mg), functional-grade in vivo monoclonal at the 1 mg size for preclinical dosing in mouse models. The pack bundles the target antibodies and the matched isotype controls your study design needs in one catalogue item, at a 5% discount to buying the vials separately.
Note: VEGF-A (B20-4.1.1) from the original spec is not currently in the catalogue and has been omitted.
What's Included IVMB0037 PD-1 (CD279) RMP1-14 Rat IgG2a, kappa 1 mg Target antibody IVMB0095 PD-L1 (B7-H1/CD274) 10F.9G2 Rat IgG2b, kappa 1 mg Target antibody IVMB0047 CTLA-4 (CD152) 9H10 Syrian Hamster IgG 1 mg Target antibody IVMB0088 LAG-3 (CD223) C9B7W Rat IgG1, kappa 1 mg Target antibody IVMB0070 CD8alpha (Ly-2) 2.43 Rat IgG2b 1 mg Target antibody IVMB0198 Rat IgG2a Isotype Control – Rat IgG2a 1 mg Matched isotype control (for PD-1 (CD279) [RMP1-14]) IVMB0200 Rat IgG2b Isotype Control – Rat IgG2b 1 mg Matched isotype control (for PD-L1 (B7-H1/CD274) [10F.9G2], CD8alpha (Ly-2) [2.43]) IVMB0378 Syrian Hamster IgG Isotype Control – Syrian Hamster IgG 1 mg Matched isotype control (for CTLA-4 (CD152) [9H10]) IVMB0196 Rat IgG1 Isotype Control – Rat IgG1 1 mg Matched isotype control (for LAG-3 (CD223) [C9B7W])
Pack Format & Pricing Pack Code: IVSP0006 Contents: 5 target antibodies + 4 matched isotype controls = 9 × 1 mg vials Format: Low Endotoxin, functional grade, mouse reactivity List Price: £1431 GBP / €1431 EUR (sum of individual 1 mg list prices) Pack Price (5% off): £1359 GBP / €1359 EUR – save £72 / €72Storage: 2–8°C up to one month; aliquot and store at -80°C for long term. Avoid repeated freeze-thaw.
Applications Recommended for: Immuno-oncology discovery, multi-checkpoint blockade, T-cell exhaustion, combination immunotherapy. Reactivity: Mouse Application class: In Vivo (depletion / blocking)
Included Products PD-1 (CD279) Code IVMB0037 Clone RMP1-14 Isotype Rat IgG2a, kappa Size 1 mg
PD-L1 (B7-H1/CD274) Code IVMB0095 Clone 10F.9G2 Isotype Rat IgG2b, kappa Size 1 mg
CTLA-4 (CD152) Code IVMB0047 Clone 9H10 Isotype Syrian Hamster IgG Size 1 mg
LAG-3 (CD223) Code IVMB0088 Clone C9B7W Isotype Rat IgG1, kappa Size 1 mg
CD8alpha (Ly-2) Code IVMB0070 Clone 2.43 Isotype Rat IgG2b Size 1 mg
Rat IgG2a Isotype Control Code IVMB0198 Clone – Isotype Rat IgG2a Size 1 mg
Rat IgG2b Isotype Control Code IVMB0200 Clone – Isotype Rat IgG2b Size 1 mg
Syrian Hamster IgG Isotype Control Code IVMB0378 Clone – Isotype Syrian Hamster IgG Size 1 mg
Rat IgG1 Isotype Control Code IVMB0196 Clone – Isotype Rat IgG1 Size 1 mg
