Blog
A Quick Guide to Myelin
The myelin sheath is an insulating layer around nerve cells. It is made up of a substance called myelin, which is produced by special cells called oligodendrocytes. Myelin protects the ner
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4th Aug 2022
A Guide To Tau Proteins & Tauopathies
This article contains an overview of protein Tau mentioning its structure, function and modifications (mutation, phosphorylation). Neurodegenerative diseases, termed Tauopathies, are discu
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20th Jul 2022
Tau proteins: An Overview
The tau protein is a hot topic in the scientific world right now. This little-known protein has been linked to Alzheimer's disease, Parkinson's disease, and other neurodegenerative disea
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27th Mar 2022
The Blood Brain Barrier: An Overview
What is the blood-brain barrier?
The Blood-brain barrier (BBB) is a system of vessels that acts as a structural and chemical barrier between the brain and the rest of the body's circula
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24th Mar 2022
Guide to Oligodendrocytes : What They Are, Functions, and Disorders
Oligodendrocytes are a type of glial cell in the central nervous system. They are responsible for myelinating axons and play an important role in nerve function and development. In t
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15th Mar 2022
Schwann Cells: Specialized Cells that Support Nerve Function
Schwann cells are cells that play a vital role in nerve function. They are responsible for myelinating axons and helping to ensure the transmission of electrical signals between neur
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14th Mar 2022
Overview: The Functions of Microglial Cells & Their Role in Neurodegenerative Disorders
Estimated reading time: 5 minutes
Microglia are immune cells that play a critical role in the brain. Microglial cells act as the first line of defence against infection and
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24th Feb 2022
How do Neurons work?
A neuron is a cell that processes and transmits information through electrical and chemical signals. There are trillions of them in the human brain, which is able to carry out so many co
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15th Jan 2022
Types of Glial Cells
Microglia
Astrocytes
Oligodendrocytes
Glial
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14th Jan 2022
Toll-like Receptor Signalling in Neurodegenerative Disease
Toll-Like Receptors
The innate immune response has come under the spotlight in recent years due to its central role in propagating the pathogen
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7th Oct 2021
Neuroimmunology: The Immune System of the CNS
The nervous and immune systems have been historically perceived as disparate entities, separated by the blood-brain barrier (BBB) with little interaction between either system. Conse
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6th Oct 2021
BDNF in inflammation and neuropathologies
BDNF Overview
Brain-derived neurotrophic factor (BDNF) is a central mediator of neuroplasticity, a term used to describe the ability of neurons
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6th Oct 2021
Neurofilament Light chain (NEFL) as a biomarker for neuronal damage
By Sinéad Kinsella PhD
NEFL Overview
Neurofilament Light chain (NEFL, or NfL) is one of three subunits of the neurofilament filaments, which are
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11th Mar 2021
From Stem Cells To Neurons: A Cnidarian Approach
By Eleni Chrysostomou, PhD Candidate, NUIG
Why do we need to know how the Nervous System develops and regenerates?
The structure and function of
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11th Mar 2021
The Ubiquitin Proteasome System in Neurodegenerative disease
By Sinead Kinsella PhD
The Ubiquitin Proteasome System (UPS)
The Ubiquitin Proteasome System (UPS) is a regulatory machinery for protein turnover in t
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10th Mar 2021