Blog
Renal and Hepatic Function Assays
Hepatic Function Assays
Liver function assays are a suite of tests designed to assess the health and efficacy of our vital
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7th Mar 2023
A Quick Guide to Myelin
The myelin sheath is an insulating layer around nerve cells. It is made up of a substance called myelin, which is produced by special cells called oligodendrocytes. Myelin protects the ner
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4th Aug 2022
The Role of Tumor Suppressor Genes in Cancer: Knudson Hypothesis & Oncogenes
The focus of this article is Tumor Suppressor Genes. There are various different types of tumor suppressor genes, with BRCA being one of the most popular. The role of Tumor Suppressor Gene
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27th Jul 2022
The Role of Zonulin In Intestinal Permeability
This article provides an overview of the protein Zonulin (function, structure, location). It describes tight junction proteins, leaky gut and Zonulin-related diseases. This includes celiac
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20th Jul 2022
Oct-4 Stem Cells & Stem Cell Differentiation
This article provides information surrounding Stem cells, with particular focus on Oct-4 Stem Cells. Additionally, stem cell pluripotency, stem cell differentiation and the potential of st
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20th Jul 2022
Spindle Assembly Checkpoint review
Spindle assembly checkpoint
The spindle assembly checkpoint (SAC), or mitotic checkpoint, is the main cell cycle control mechanism that governs m
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26th Apr 2022
The Exciting Field of Stem Cell Research
What are Stem Cells?
Stem cells are primitive, undifferentiated, and unspecialised cells that are found in multicellular organisms
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21st Jan 2022
Inflammation and the aging process
by Ryan Wallis, PhD
Aging and Disease
Imagine a world where everything you do is missing just a little piece and as time goes on you start to lose sense entirely.
This is the deva
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20th Jan 2022
TNF alpha & Inflammation
TNF Alpha Overview
Tumour necrosis factor alpha (TNF alpha) is a 26 kDa transmembrane protein and a member of the TNF superfamily, with i
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6th Oct 2021
CRISPR-Cas Screening for Cell Viability
Key Points
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is a method of gene editing that uses t
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28th Sep 2021
Follicle Stem Cell Behaviour
David Melamed, Phd Candidate, Colombia University
When I started in the Kalderon Lab five years ago, I had no idea that our work would lead us to drastical
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11th Mar 2021
Cytokinesis review
By John Bannon PhD
Early Cytokinesis
Early cytokinesis; from anaphase to midbody formation cytokinesis is the physical s
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11th Mar 2021
Microtubule and Mitosis review
Introduction
Microtubules are key components of the cytoskeleton and are composed of alpha and beta tubulin. These dimerise in a head to tail fashion to fo
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11th Mar 2021
A broccoli juice a day keep the heart attack away
Alex Lloyd PhD Candidate, Dublin Institute of Technology
Did you know that roughly 17.5 million people worldwide die annually from Cardiovascular diseases
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10th Mar 2021
Do you know…migraines affect more than 10% of the world population?
By Francisco Algaba Chueco
In this post we discuss a topic that everyone will have heard of. Let’s talk about migraines, a disorder that hides a huge ph
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10th Mar 2021
Metabolism or pluripotency – which regulates which? A chicken or the egg story.
By Sophie Arthur
How many diseases and conditions do you think exist in this world? Thousands? Hundreds of thousands? Maybe even millions? Unfortunately, I don’t know the answer. But what I
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10th Mar 2021
Investigating orthohantavirus infections with proteomics
Sarah Brun Bar-Yaacov PhD Candidate, University of Liverpool
Orthohantaviruses are a group of segmented negative-sense RNA viruses maintained as asympto
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10th Mar 2021
An insight into the topology of the Enteric Nervous System
The Enteric Nervous system (ENS) is one of the largest subdivisions of the Peripheral Nervous System. This remarkable system is embedded between sheets of smooth muscle cells of the intestinal
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10th Mar 2021
Mitotic Catastrophe Review
Hallmarks of mitotic catastrophe
The hallmarks of mitotic catastrophe were first recognised in a series of papers published by Spear and Glucksmann during
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9th Mar 2021
Sensing Danger: The Biology of TLR-Mediated Inflammation
By Eoin Mac Réamoinn
Toll-like receptors (TLRs) are renowned for their fundamental roles in innate sensing and initiating inflammatory responses. TLRs
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8th Mar 2021
Inhibiting cell division
Unregulated cell growthCancer, although heterogeneous by its very nature, can be broadly defined as a set of diseases characterised by unregulated cell growth leading to invasion of surround
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18th Dec 2020
Spotlight on Mitochondria
Throughout my graduate and postgraduate studies I have been really intrigued and fascinated by the mitochondria, the organelle that keeps all of us running everyday! The more I learn about
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18th Dec 2020
Zebrafish against cretinism and hypotonia
By Natalia Siomava, PhD
Cretinism is a severe medical condition of intellectual disability caused by the deficiency of thyroid hormone (congenital hypothyroi
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18th Dec 2020
Epigenetic modifiication & Histone methylation
Agata Miezaniec PhD Candidate, University of Nottingham, UK
Epigenetics and the link to DNA Methylation
The term ‘Epigenet
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1st Jan 1970