Ankyrin repeat and SOCS box protein 13(ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Product Name:
Human ASB13 Recombinant Protein (RPES2580)
Product Code:
RPES2580
Size:
10µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
Ankyrin repeat and SOCS box protein 13, ASB13,
Accession:
Q8WXK3
Sequence:
Met 1-Asn278
Fusion tag:
N-6His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Ankyrin repeat and SOCS box protein 13 is produced by our E.coli expression system and the target gene encoding Met1-Asn278 is expressed with a 6His tag at the N-terminus.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
31.4 kDa
AP Mol Mass:
28 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of PBS, pH 7.4, 4M Urea.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
