Human ASB13 Recombinant Protein (RPES2580)
- SKU:
- RPES2580
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Signal Transduction
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Description
system_update_altDatasheet
Human ASB13 Recombinant Protein
Ankyrin repeat and SOCS box protein 13(ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
| Product Name: | Human ASB13 Recombinant Protein (RPES2580) |
| Product Code: | RPES2580 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Ankyrin repeat and SOCS box protein 13, ASB13, |
| Accession: | Q8WXK3 |
| Sequence: | Met 1-Asn278 |
| Fusion tag: | N-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Ankyrin repeat and SOCS box protein 13 is produced by our E.coli expression system and the target gene encoding Met1-Asn278 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 31.4 kDa |
| AP Mol Mass: | 28 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of PBS, pH 7.4, 4M Urea. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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