C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL11 activates eosinophils, a hallmark of allergic responses when allergens are detected. CCL11's actions are regulated by its interaction with a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. CCL11, on the other hand, has been discovered to have a high degree of selectivity for its receptor, with inactive receptors present on neutrophils and monocytes that do not express CCR3. Human CCL11/Eotaxin Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
Human CCL11/Eotaxin Recombinant Protein (RPES4715)
Recombinant Human C-C Motif Chemokine 11 is produced by our E.coli expression system and the target gene encoding Gly24-Pro97 is expressed.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
8.6 kDa
AP Mol Mass:
14 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl?pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
